Evidence map›Paper›PMID 37938415›Full record

ArticleLangenbeck's archives of surgery2023

Validation study for prognostic scoring system for perihilar cholangiocarcinoma surgery using preoperative factors.

Yuma Aoki, Takehiro Noji, Kimitaka Tanaka, Aya Matsui, Yoshitsugu Nakanishi, Toshimichi Asano, Toru Nakamura, Takahiro Tsuchikawa, Satoshi Hirano

Abstract read
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In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuma AokiDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Takehiro NojiDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan. drnoji@med.hokudai.ac.jp.
Kimitaka TanakaDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Aya MatsuiDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Yoshitsugu NakanishiDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Toshimichi AsanoDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Toru NakamuraDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Takahiro TsuchikawaDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.
Satoshi HiranoDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Kita-15, Nishi 7, Kita-Ku, Sapporo, 060-8638, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecently, systemic inflammatory responses (SIR) have been shown to play a pivotal role in the development and progression of cancer. We previously reported that four factors, serum carcinoembryonic antigen (> 7 ng/dL), serum albumin (< 3.5 g/dL), C-reactive protein (> 0.5 mg/dL), and platelet-lymphocyte ratio (PLR; > 150), were independent prognostic factors after perihilar cholangiocarcinoma (PHCC) surgery. We also advocated a prognosis predictive preoperative prognostic score (PPS) using these four factors and showed that PPS could predict patients' prognosis on survival. This retrospective study sought to validate preoperatively available prognostic factors for survival after major hepatectomy as reported previously, including PPS for PHCC.

methodsWe retrospectively validated our PPS score and reported SIR scoring systems using the data of 125 consecutive patients who underwent PHCC surgery from January 2010 to November 2020.

resultsPPS was an independent preoperative prognostic factors for survival. The T and N categories were independent prognostic factors. Other SIR scores were not independent preoperative factors in the univariate analysis. Among SIR scores, only the PPS was found to be associated with OS and disease-free survival. The PPS was also associated with histopathological factors (T and N categories).

conclusionPPS could be useful in predicting long-term survival after PHCC and may be a more useful scoring system than other SIR systems.

Indexed as

Bile Duct NeoplasmsKlatskin TumorC-Reactive ProteinHumansPrognosisRetrospective StudiesC-Reactive ProteinPerihilar cholangiocarcinomaPlatelet-lymphocyte ratioPrognostic predicting scoreSystematic inflammatory response

Identifiers

PMID37938415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.