Evidence map›Paper›PMID 37938350›Full record

ArticleEuropean biophysics journal : EBJ2023

Annexin A5 stabilizes matrix vesicle-biomimetic lipid membranes: unravelling a new role of annexins in calcification.

Claudio R Ferreira, Marcos Antônio E Cruz, Maytê Bolean, Luiz Henrique da S Andrilli, José Luis Millan, Ana Paula Ramos, Massimo Bottini, Pietro Ciancaglini

Open access · hybridAbstract read
In one paragraph

Article in European biophysics journal : EBJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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  7. Annexin A5 ameliorates HMolecular biology reports · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Claudio R FerreiraDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil.
Marcos Antônio E CruzDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil.
Maytê BoleanDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil.
Luiz Henrique da S AndrilliDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil.
José Luis MillanSanford Burnham Prebys, La Jolla, CA, 92037, USA.
Ana Paula RamosDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil.
Massimo BottiniDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil. massimo.bottini@uniroma2.it.
Pietro CiancagliniDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo (FFCLRP-USP), Ribeirão Preto, São Paulo, Brazil. pietro@ffclrp.usp.br.ORCID http://orcid.org/0000-0002-2785-1345
Universidade de Ribeirão Preto · BRUniversity of Rome Tor Vergata · ITSanford Burnham Prebys Medical Discovery Institute · US

Funding

CAPES 2020-88887.569449/2020-00CAPES Finance Code 001CNPq 305426/2021-4FAPESP 2019/08568-2FAPESP 2019/25054-2FAPESP 2021/13140-1
6 · The paper itself

Abstract

Matrix vesicles are a special class of extracellular vesicles thought to actively contribute to both physiologic and pathologic mineralization. Proteomic studies have shown that matrix vesicles possess high amounts of annexin A5, suggesting that the protein might have multiple roles at the sites of calcification. Currently, Annexin A5 is thought to promote the nucleation of apatitic minerals close to the inner leaflet of the matrix vesicles' membrane enriched in phosphatidylserine and Ca

Indexed as

AnnexinsLiposomesAnnexin A5BiomimeticsCalciumPhosphatidylserinesProteomicsAnnexin A5AnnexinsCalciumLiposomesPhosphatidylserinesAnnexin A5Ca2+CalorimetryFluorescent microscopyLipid membranePhosphatidylserine

Identifiers

PMID37938350
PMCPMC10682239
OpenAlexW4388500419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.