ArticleISME communications2022
Experimental transmission of Stony Coral Tissue Loss Disease results in differential microbial responses within coral mucus and tissue.
Article in ISME communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Runaway coral-algal dysbiosis may be responsible for rapid coral tissue loss.Scientific reports · 2026Article
- Symbiont Identity Impacts Prokaryotic Microbiome Dynamics During Heat Stress in a Model System for Corals.Integrative and comparative biology · 2026Article
- Microbial Communities Vary by Body Region but Remain Consistent Across Color Morphs in the Solitary AscidianInternational journal of microbiology · 2026Article
- Key coral symbiont lineages (family Symbiodiniaceae) are differentially associated with stony coral tissue loss disease.ISME communications · 2026Article
- Stony Coral Tissue Loss Disease Results in Persistent Microbial-Level Disturbances on Coral Reef Ecosystems.Environmental microbiology reports · 2025Article
- Machine learning reveals distinct gene expression signatures across tissue states in stony coral tissue loss disease.Royal Society open science · 2025Article
- Resolving Symbiodiniaceae Diversity Across Coral Microhabitats and Reef Niches.Environmental microbiology · 2025Article
- Influence of Temperature and Saline Conditions on Bacteria Naturally Associated With the Cnidarian HostInternational journal of microbiology · 2025Article
- Sediment exposure decreases diversity in the surface mucus layer microbiome ofFrontiers in microbiology · 2025Article
- Shifts in the microbiome and virome are associated with stony coral tissue loss disease (SCTLD).ISME communications · 2025Article
- Tank-based bacterial profiling identifies basin-wide white band disease pathogen candidate and no bacterial associations with coral disease resistance.ISME communications · 2025Article
- Prior heat stress increases pathogen susceptibility in the model cnidarian Exaiptasia diaphana.Communications biology · 2024Article
- Negative parental and offspring environmental effects of macroalgae on coral recruitment are linked with alterations in the coral larval microbiome.Royal Society open science · 2024Article
- Novel metagenomics analysis of stony coral tissue loss disease.bioRxiv : the preprint server for biology · 2024Article
- Microbial shifts associated to ENSO-derived thermal anomalies reveal coral acclimation at holobiont level.Scientific reports · 2023Article
- Filamentous virus-like particles are present in coral dinoflagellates across genera and ocean basins.The ISME journal · 2023Article
- Shifts in the coral microbiome in response toApplied and environmental microbiology · 2023Article
- Microorganisms and dissolved metabolites distinguish Florida's Coral Reef habitats.PNAS nexus · 2023Article
- The Impact of Highly Weathered Oil from the Most Extensive Oil Spill in Tropical Oceans (Brazil) on the Microbiome of the CoralMicroorganisms · 2023Article
- Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae.Nature communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Stony coral tissue loss disease (SCTLD) is a widespread and deadly disease that affects nearly half of Caribbean coral species. To understand the microbial community response to this disease, we performed a disease transmission experiment on US Virgin Island (USVI) corals, exposing six species of coral with varying susceptibility to SCTLD. The microbial community of the surface mucus and tissue layers were examined separately using a small subunit ribosomal RNA gene-based sequencing approach, and data were analyzed to identify microbial community shifts following disease acquisition, potential causative pathogens, as well as compare microbiota composition to field-based corals from the USVI and Florida outbreaks. While all species displayed similar microbiome composition with disease acquisition, microbiome similarity patterns differed by both species and mucus or tissue microhabitat. Further, disease exposed but not lesioned corals harbored a mucus microbial community similar to those showing disease signs, suggesting that mucus may serve as an early warning detection for the onset of SCTLD. Like other SCTLD studies in Florida, Rhodobacteraceae, Arcobacteraceae, Desulfovibrionaceae, Peptostreptococcaceae, Fusibacter, Marinifilaceae, and Vibrionaceae dominated diseased corals. This study demonstrates the differential response of the mucus and tissue microorganisms to SCTLD and suggests that mucus microorganisms may be diagnostic for early disease exposure.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.