Evidence map›Paper›PMID 37937904›Full record

ArticleDemography2023

Barker's Hypothesis Among the Global Poor: Positive Long-Term Cardiovascular Effects of in Utero Famine Exposure.

Alberto Ciancio, Jere Behrman, Fabrice Kämpfen, Iliana V Kohler, Jürgen Maurer, Victor Mwapasa, Hans-Peter Kohler

Open access · diamondAbstract read
In one paragraph

Article in Demography, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Alberto CiancioAdam Smith Business School, University of Glasgow, Glasgow, UK.ORCID 0000-0001-5346-0885
Jere BehrmanDepartment of Economics, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-7835-6283
Fabrice KämpfenSchool of Economics, University College Dublin, Dublin, Ireland.ORCID 0000-0001-7304-7473
Iliana V KohlerPopulation Studies Center, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-5114-546X
Jürgen MaurerDepartment of Economics, University of Lausanne, Lausanne, Switzerland.
Victor MwapasaKamuzu University of Health Sciences, Zomba, Malawi.ORCID 0000-0002-2748-8902
Hans-Peter KohlerPopulation Studies Center, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0003-0639-4349
University City Science Center · USAdam Smith Institute · GBKamuzu Central Hospital · MWUniversity College Dublin · IEUniversity of Lausanne · CHUniversity of Pennsylvania · US

Funding

STATISTICAL DATA ENCLAVE COREP30AG012836 · NIA · UNIVERSITY OF PENNSYLVANIA · PI COE, NORMA B, KOHLER, HANS-PETER · 1999 to 2024
$14.0M
Population Science Research Center Development CoreR24HD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI SMITH, HERBERT L. · 2003 to 2017
$9.8M
Sci-Tech Core-Population Dynamics Research CenterP2CHD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI EMILIO ALBERTO PARRADO · 2018 to 2026
$5.3M
Surviving an Epidemic: Families and Well-Being, Malawi 1998-2020R01HD087391 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI ANGLEWICZ, PHILIP ANTHONY, KOHLER, HANS-PETER · 2017 to 2022
$2.9M
Consequences of High Morbidity and Mortality in a Low-Income CountryR01HD053781 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2007 to 2011
$2.9M
Role of androgens in age-related changes in pain and analgesiaR21AG053783 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RO, JIN Y · 2016 to 2017
$424k
The Benefits of Knowledge: Mortality Risks, Mental health and Life-Cycle BehaviorsR21AG053763 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DELAVANDE, ADELINE, KOHLER, HANS-PETER · 2016 to 2017
$398k
Leveraging Social Networks and Linkage to Care to Foster Healthy Aging in a Low-Income ContextR03AG069817 · NIA · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, ILIANA V · 2020 to 2021
$162k
NIA NIH HHS P30 AG012836NIA NIH HHS R03 AG069817NIA NIH HHS R21 AG053763NIA NIH HHS R21 AG053783NICHD NIH HHS P2C HD044964NICHD NIH HHS R01 HD053781NICHD NIH HHS R01 HD087391NICHD NIH HHS R24 HD044964
6 · The paper itself

Abstract

An influential literature on the Developmental Origins of Health and Disease (DOHaD) has documented that poor conditions in utero lead to higher risk of cardiovascular disease at older ages. Evidence from low-income countries (LICs) has hitherto been missing, despite the fact that adverse in utero conditions are far more common in LICs. We find that Malawians exposed in utero to the 1949 Nyasaland famine have better cardiovascular health 70 years later. These findings highlight the potential context specificity of the DOHaD hypothesis, with in utero adversity having different health implications among aging LIC individuals who were exposed to persistent poverty.

Indexed as

Cardiovascular DiseasesFaminePrenatal Exposure Delayed EffectsAgingFemaleHumansSouthern African PeopleBarker hypothesisCardiovascular healthDevelopmental origins of health and diseaseEarly-life influence on later-life healthSub-Saharan Africa

Identifiers

PMID37937904
PMCPMC10875974
OpenAlexW4388490509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.