Evidence map›Paper›PMID 37937475›Full record

ArticleJournal of veterinary internal medicine

Accuracy of Crit-Line® monitors in predicting hematocrit and change in blood volume of dogs during hemodialysis.

Whitney E Vickery, Sarah M L Steinbach, George E Moore

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Whitney E VickeryDepartment of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.ORCID https://orcid.org/0009-0007-6829-8682
Sarah M L SteinbachDepartment of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.ORCID https://orcid.org/0000-0002-9226-6804
George E MooreDepartment of Veterinary Administration, Purdue University, West Lafayette, IN, USA.ORCID https://orcid.org/0000-0001-7473-3387
Purdue University West Lafayette · USUnited States Army Medical Command · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUltrafiltration (UF) is an extracorporeal technique for treating fluid overload and is monitored with noninvasive blood volume monitors. HYPOTHESIS/

objectivesThe primary objective was to determine the accuracy of Crit-Line® III and IV noninvasive blood volume monitors to estimate canine packed cell volume (PCV) and changes in blood volume during UF. A secondary aim was to determine accuracy of targeted ultrafiltration rates (UFR) compared to calculated delivered UFR.

methodsAn ex vivo study with a single Phoenix® X36 platform and canine packed red blood cells (pRBC) was performed. Through dilution and UF, clinically applicable PCV values were obtained and compared to Crit-Line® hematocrit (Hct). Blood volume was constantly measured and compared to targeted UFR. Systematic and proportional bias were calculated using a Bayes method.

resultsCrit-Line® III and IV reported Hct was significantly lower than PCV (n = 140, median 26%, range, 8%-50%) when PCV was >25% and >30%, respectively. Crit-Line® III and IV calculated change in blood volume (ΔBV%) was significantly different from measured blood volume changes at ΔBV% ±20% and >-20%, respectively. Comparing targeted and delivered UFR (mL/h), less than targeted UFR was removed at UFR100 through UFR400 and UFR0 adding volume. CONCLUSIONS AND CLINICAL IMPORTANCE: Crit-Line® III and IV monitors provide accurate estimates of canine PCV and UF volume change within specific ranges and are useful in monitoring canine UF and hemodialysis. Veterinary hemodialysis services should evaluate individual machines for UFR inaccuracies, which can meaningfully affect small animals.

Indexed as

Blood VolumeRenal DialysisAnimalsBayes TheoremDogsHematocritacute kidney injuryfluid overloadintradialytic morbid eventpacked cell volumeultrafiltration

Identifiers

PMID37937475
PMCPMC10658494
OpenAlexW4388493516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.