Evidence map›Paper›PMID 37937365›Full record

ArticleStatistical methods in medical research2023

A support vector machine-based cure rate model for interval censored data.

Suvra Pal, Yingwei Peng, Wisdom Aselisewine, Sandip Barui

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Modeling Cure from Cancer Accounting for Inevitable Mortality.Journal of the Royal Statistical Society. Series C, Applied statistics · 2026
    Article
  3. Fitting high-dimensional mixture cure models using the hdcuremodelsR package.Computer methods and programs in biomedicine · 2026
    Article
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  7. Machine Learning Approach for Analyzing Mixed Case Interval Censored Data with a Cured Subgroup.Advances in statistical analysis : AStA : a journal of the German Statistical Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suvra PalDepartment of Mathematics, University of Texas at Arlington, TX, USA.ORCID 0000-0001-9864-9489
Yingwei PengDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Wisdom AselisewineDepartment of Mathematics, University of Texas at Arlington, TX, USA.
Sandip BaruiQuantitative Methods and Operations Management Area, Indian Institute of Management Kozhikode, Kozhikode, KL, India.

Funding

Using Machine Learning to Improve the Predictive Accuracy of Disease CureR15GM150091 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI PAL, SUVRA · 2023 to 2023
$452k
NIGMS NIH HHS R15 GM150091
6 · The paper itself

Abstract

The mixture cure rate model is the most commonly used cure rate model in the literature. In the context of mixture cure rate model, the standard approach to model the effect of covariates on the cured or uncured probability is to use a logistic function. This readily implies that the boundary classifying the cured and uncured subjects is linear. In this article, we propose a new mixture cure rate model based on interval censored data that uses the support vector machine to model the effect of covariates on the uncured or the cured probability (i.e. on the incidence part of the model). Our proposed model inherits the features of the support vector machine and provides flexibility to capture classification boundaries that are nonlinear and more complex. The latency part is modeled by a proportional hazards structure with an unspecified baseline hazard function. We develop an estimation procedure based on the expectation maximization algorithm to estimate the cured/uncured probability and the latency model parameters. Our simulation study results show that the proposed model performs better in capturing complex classification boundaries when compared to both logistic regression-based and spline regression-based mixture cure rate models. We also show that our model's ability to capture complex classification boundaries improve the estimation results corresponding to the latency part of the model. For illustrative purpose, we present our analysis by applying the proposed methodology to the NASA's Hypobaric Decompression Sickness Database.

Indexed as

Models, StatisticalSupport Vector MachineAlgorithmsComputer SimulationHumansProportional Hazards ModelsSurvival Analysisexpectation–maximization algorithmmixture cure rate modelmultiple imputationsequential minimal optimizationSupport vector machine

Identifiers

PMID37937365
PMCPMC10710011

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.