Evidence map›Paper›PMID 37937174›Full record

ArticleKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2023

Effects of hypoxia versus ischaemia on vascular functions of isolated rat thoracic aorta: revisiting the

Halit Güner Orhan, Ariyan Teimoori, Elif Demirtaş, Nargiz Zeynalova, Oğuzhan Ekin Efe, Selda Emre Aydingöz

Open access · diamondAbstract read
In one paragraph

Article in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Halit Güner OrhanDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Ariyan TeimooriDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Elif DemirtaşDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Nargiz ZeynalovaDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Oğuzhan Ekin EfeDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Selda Emre AydingözDepartment of Medical Pharmacology, Başkent University Faculty of Medicine, Ankara, Turkey.
Başkent University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Aim: To compare the effects of hypoxia and ischaemia, with or without reperfusion, on the vascular functions of isolated thoracic aortic rings of rats. Material and methods: Thoracic aortas of 12 male Sprague-Dawley rats (350-500 g, 18-24 months old) were isolated and divided into rings that were randomly allocated to control, ischaemia, hypoxia, ischaemia-reperfusion, and hypoxia-reperfusion groups. Aortic rings other than those of the control group were stored at 4°C for 24 h in saline. For ischaemia, saline was gassed with nitrogen. After 24 h, aortic rings in the ischaemia-reperfusion and hypoxia-reperfusion groups were incubated with 200 μM sodium hypochlorite for 30 min. Vascular and endothelial functions were tested in an organ bath set-up. Results: Vascular response to potassium chloride (80 mM) decreased in all experimental groups compared to the control group ( Conclusions: Ischaemia followed by reperfusion should be implanted to achieve maximum endothelial and contractile dysfunction

Indexed as

endothelial functionhypoxiain vitroischaemiareperfusion

Identifiers

PMID37937174
PMCPMC10626406
OpenAlexW4388095750

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.