Evidence map›Paper›PMID 37937162›Full record

ArticleJournal of contemporary pharmacy practice2022

Gaps in Patient Education on Safe Handling and Disposal of Oral Chemotherapy Drugs: A Pilot Prospective Cohort Survey Study.

Sun Yang, Priya Patel, Alexandra Corcoran, Eric Dobberpuhl, Samantha Isidro, Dustin Le, Analise Klassen, Jay Rho, David Tran, Richard Beuttler and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of contemporary pharmacy practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sun Yangdepartment of pharmacy practice at Chapman University School of Pharmacy in Irvine, California.ORCID 0000-0002-8463-7468
Priya PatelChapman University School of Pharmacy, Irvine.
Alexandra CorcoranPomona Valley Hospital Medical Center in Pomona, California.
Eric DobberpuhlErnest Mario School of Pharmacy at Rutgers, the State University of New Jersey, Piscataway, New Jersey.
Samantha IsidroCVS store # 16045 in Garden Grove, California.
Dustin LeCommon Spirit Health St. Joseph Medical Center of Stockton and Thomas J. Long School of Pharmacy and Health Sciences.
Analise KlassenChapman University School of Pharmacy during the project.
Jay RhoChapman University School of Pharmacy during the project.
David TranChapman University School of Pharmacy during the project.
Richard Beuttlerdepartment of biomedical and pharmaceutical sciences at Chapman University School of Pharmacy.ORCID 0000-0001-8397-3438
Neda Noori Nassrdepartment of clinical pharmacy at the University of California, San Francisco, School of Pharmacy.
Katherine GruenbergUniversity of California, San Francisco, School of Pharmacy.ORCID 0000-0003-2552-353X
Siu-Fun Wongresearch scientist, department of pharmacy practice at Chapman University School of Pharmacy and a clinical professor (volunteer) in the division of hematology/oncology, department of medicine at the University of California, Irvine, Health in Orange, California.ORCID 0000-0003-3884-2863
University of California, San Francisco · US

Funding

The Development of Novel Mechanistically-based APE/Ref-1 Redox InhibitorsK08CA179084 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI YANG, SUN · 2014 to 2018
$569k
NCI NIH HHS K08 CA179084
6 · The paper itself

Abstract

Background: Oral anticancer chemotherapy (OC) has been misperceived as being safer than intravenous chemotherapy, leading to its increased risk of improper handling and disposal. This survey study assessed the knowledge, practices and attitudes of pharmacists and patients regarding OC handling and disposal, gaps in knowledge and barriers to patient education. Methods: Surveys were developed based on literature review and pilot study validation results. Patients completed a 33-item paper or electronic survey whereas pharmacists completed a 38-item electronic survey. Descriptive statistics and Fisher's exact test computed using the R Project were used for analyses. Results: Pharmacist group (16/25, 62.5%) and patient group (14/29, 48.3%) believed that the oral route is safer than IV. Average overall correct response rates for pharmacist and patient groups were 78.3% and 61.9%, respectively. Significant gaps in knowledge between groups were observed in three sections (p < 0.05). Common barriers to providing patient education were insufficient training (70.8%) and insufficient time (50%). Conclusion: Pharmacist and patient knowledge, awareness and practices of OC safe handling and disposal are suboptimal. Areas of knowledge gaps and barriers to patient education were identified. Enhanced supports are needed to empower pharmacists to assume an active role in patient education on safe handling and disposal of OC.

Identifiers

PMID37937162
PMCPMC10629833
OpenAlexW4388500707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.