Evidence map›Paper›PMID 37937122›Full record

ArticlePulmonary circulation2023

Management of pulmonary hypertension associated with valvular heart disease with angiotensin-receptor neprilysin inhibitor.

Hyeon-Ju Ryoo Ali, Jerome Thomas, Sandeep Sahay, Ashrith Guha

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hyeon-Ju Ryoo AliDepartment of Cardiology The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID 0000-0002-3378-9154
Jerome ThomasDepartment of Cardiology Austin Heart Austin Texas USA.
Sandeep SahayDepartment of Pulmonology Houston Methodist Hospital Houston Texas USA.ORCID 0000-0002-0672-1680
Ashrith GuhaDepartment of Cardiology Houston Methodist Hospital Houston Texas USA.
Methodist Hospital · USAustin Regional Clinic · USThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension secondary to left-sided valvular disease (VHD-PH) is associated with high morbidity and mortality. Angiotensin-receptor neprilysin inhibitor (ARNI) is a novel pharmacotherapy, which reduces afterload with natriuresis and peripheral vasodilation. Our cases demonstrate that ARNI may also have a role in the treatment of combined pre- and postcapillary pulmonary hypertension that is independent of its effect on pulmonary capillary wedge pressure and cardiac output. Future prospective trials are needed to evaluate role of ARNIs in treatment of VHD-PH.

Indexed as

cardiopulmonary pharmacology and therapeuticscongestive heart failurehemodynamicspulmonary hypertension

Identifiers

PMID37937122
PMCPMC10626127
OpenAlexW4388426267

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.