Evidence map›Paper›PMID 37937091›Full record

ArticleHSS journal : the musculoskeletal journal of Hospital for Special Surgery2023

Neonatal Hip Loading in Developmental Dysplasia: Finite Element Simulation of Proximal Femur Growth and Treatment.

S Mahsa Sadeghian, Owen J Arthurs, Xinshan Li, Cara L Lewis, Sandra J Shefelbine

Open access · greenAbstract read
In one paragraph

Article in HSS journal : the musculoskeletal journal of Hospital for Special Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

S Mahsa SadeghianDepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA, USA.
Owen J ArthursDepartment of Radiology, Great Ormond Street Hospital, London, UK.
Xinshan LiDepartment of Mechanical Engineering, Insigneo Institute for in silico Medicine, University of Sheffield, Sheffield, UK.
Cara L LewisDepartment of Physical Therapy, College of Health & Rehabilitation Sciences: Sargent College, Boston University, Boston, MA, USA.ORCID https://orcid.org/0000-0002-9888-4902
Sandra J ShefelbineDepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA, USA.
Northeastern University · USBoston University · USGreat Ormond Street Hospital · GBInsigneo · GB

Funding

Medical Research Council MR/R002118/1
6 · The paper itself

Abstract

Background: Abnormal prenatal hip joint loading can lead to compromised hip joint function. Early intervention is crucial for favorable outcomes. Purpose: This study investigates the impact of treatment timing (initiation and duration) on cartilage growth and ossification in the proximal femur of infants with developmental dysplasia of the hip, a condition affecting newborns. Methods: We used a mechanobiological model to simulate proximal femur growth during treatment durations of 3 months, 6 months, and a late-start treatment. Results: The findings indicate that the timing of treatment initiation is crucial, while a longer treatment duration does not contribute to improved morphological development of the hip joint. Conclusions: Mechanobiological models of growth can be used to develop treatments and therapies that correct loading conditions. Growing bone is particularly sensitive to loading conditions, and altered loading during growth can affect bone shape and functionality.

Indexed as

bone growthdevelopmental dysplasia of the hipfinite element modelmechanobiologyPavlik harness

Identifiers

PMID37937091
PMCPMC10626923
OpenAlexW4386709729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.