Evidence map›Paper›PMID 37937017›Full record

ArticleCureus2023

Pediatric Lupus Retinopathy: A Rare Manifestation of a Grave Systemic Disorder.

Shweta Parakh, Vaibhav Bhatt, Shrutanjoy Das, Abhijaat Chaturvedi, Gaurav Luthra, Deeksha Katoch, Prabal Barman, Ankur K Jindal, Saurabh Luthra

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shweta ParakhOphthalmology, Drishti Eye Institute, Dehradun, IND.
Vaibhav BhattOphthalmology, Drishti Eye Institute, Dehradun, IND.
Shrutanjoy DasOphthalmology, Drishti Eye Institute, Dehradun, IND.
Abhijaat ChaturvediOphthalmology, Drishti Eye Institute, Dehradun, IND.
Gaurav LuthraOphthalmology, Drishti Eye Institute, Dehradun, IND.
Deeksha KatochOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Prabal BarmanPediatric Rheumatology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Ankur K JindalPediatric Rheumatology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Saurabh LuthraOphthalmology, Drishti Eye Institute, Dehradun, IND.
Post Graduate Institute of Medical Education and Research · INMidwest Eye Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a rare case of pediatric systemic lupus erythematosus (pSLE) and its successful management. A nine-year-old female presented with bilateral diminution of vision, fever, and rash in the malar region, chest, abdomen, back, and arms for three months. Clinical examination and multimodal imaging revealed bilateral extensive retinal vasculitis with macular edema. Laboratory investigations revealed anemia, leucopenia, positive serum antinuclear antibody (ANA), and anti-extractable nuclear antigen (ENA) antibodies. A diagnosis of pediatric lupus retinopathy was made. Ocular and systemic manifestations responded well to intense systemic immunosuppression (pulse intravenous {IV} methylprednisolone, oral prednisolone and hydroxychloroquine {HCQ}, six cycles of IV cyclophosphamide, and oral azathioprine) along with topical steroids and laser photocoagulation, over the next 10 months. Though ocular manifestations are not a part of the diagnostic criteria for SLE, they may be markers of active systemic disease. Ophthalmologists and rheumatologists must treat this complex disease in tandem in order to provide optimum patient care.

Indexed as

anti-extractable nuclear antigen (ena) antibodiesantinuclear antibody (ana)immunosuppressionpediatric lupus retinopathypediatric systemic lupus erythematosus (psle)vasculopathy

Identifiers

PMID37937017
PMCPMC10626398
OpenAlexW4387426573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.