Evidence map›Paper›PMID 37936983›Full record

ArticleFrontiers in cell and developmental biology2023

Native lamin A/C proteomes and novel partners from heart and skeletal muscle in a mouse chronic inflammation model of human frailty.

Fatima D Elzamzami, Arushi Samal, Adith S Arun, Tejas Dharmaraj, Neeti R Prasad, Alex Rendon-Jonguitud, Lauren DeVine, Jeremy D Walston, Robert N Cole, Katherine L Wilson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. FAM210A: An emerging regulator of mitochondrial homeostasis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Fatima D Elzamzami *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Arushi Samal *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Adith S Arun *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Tejas Dharmaraj *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Neeti R PrasadDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Alex Rendon-JonguitudDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Lauren DeVineDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Jeremy D WalstonDivision of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Robert N ColeDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Katherine L WilsonDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
NIA NIH HHS P30 AG021334
6 · The paper itself

Abstract

Clinical frailty affects ∼10% of people over age 65 and is studied in a chronically inflamed (Interleukin-10 knockout; "IL10-KO") mouse model. Frailty phenotypes overlap the spectrum of diseases ("laminopathies") caused by mutations in

Indexed as

AldoAEmery-Dreifuss muscular dystrophyFam210alamin ALmcd1Perm1Phf2Tmem38a

Identifiers

PMID37936983
PMCPMC10626543
OpenAlexW4387879333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.