Evidence map›Paper›PMID 37936922›Full record

ArticleFASEB bioAdvances2023

Biological effects of air pollution on the function of human skin equivalents.

Wil J Reynolds, Ndubuisi Eje, Paul Christensen, Wen-Hwa Li, Susan M Daly, Ramine Parsa, Bhaven Chavan, Mark A Birch-Machin

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Cutaneous Redox Senescence.Biomedicines · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Wil J ReynoldsDermatological Sciences, Institute of Translational and Clinical Research Newcastle University Newcastle upon Tyne UK.ORCID https://orcid.org/0009-0005-8840-7415
Ndubuisi EjeBedson Building, Newcastle University Newcastle upon Tyne UK.ORCID https://orcid.org/0009-0001-7521-1713
Paul ChristensenBedson Building, Newcastle University Newcastle upon Tyne UK.ORCID https://orcid.org/0000-0002-4974-2000
Wen-Hwa LiJohnson and Johnson Consumer Inc. Skillman New Jersey USA.ORCID https://orcid.org/0000-0002-2569-6863
Susan M DalyJohnson and Johnson Consumer Inc. Skillman New Jersey USA.ORCID https://orcid.org/0009-0004-7461-0669
Ramine ParsaJohnson and Johnson Consumer Inc. Skillman New Jersey USA.ORCID https://orcid.org/0000-0001-5753-7771
Bhaven ChavanCroda Europe Ltd Snaith UK.ORCID https://orcid.org/0009-0002-0165-683X
Mark A Birch-MachinDermatological Sciences, Institute of Translational and Clinical Research Newcastle University Newcastle upon Tyne UK.ORCID https://orcid.org/0000-0002-2668-2623
Newcastle University · GBJohnson & Johnson (United States) · USCroda (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization reports that 99% of the global population are exposed to pollution levels higher than the recommended air quality guidelines. Pollution-induced changes in the skin have begun to surface; however, the effects require further investigation so that effective protective strategies can be developed. This study aimed to investigate some of the aging-associated effects caused by ozone and particulate matter (PM) on human skin equivalents. Full-thickness skin equivalents were exposed to 0.01 μg/μL PM, 0.05 μg/μL PM, 0.3 ppm ozone, or a combination of 0.01 μg/μL PM and 0.3 ppm ozone, before skin equivalents and culture medium were harvested for histological/immunohistochemical staining, gene and protein expression analysis using qPCR, Western blotting, and ELISA. Markers include MMP-1, MMP-3,

Indexed as

agingin vitroozoneparticulate matterpollutionskin

Identifiers

PMID37936922
PMCPMC10626160
OpenAlexW4387340623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.