Evidence map›Paper›PMID 37936893›Full record

ArticleRegenerative biomaterials2023

Micro-porous PLGA/

Luan P Hatt, Sylvie Wirth, Aapo Ristaniemi, Daniel J Ciric, Keith Thompson, David Eglin, Martin J Stoddart, Angela R Armiento

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luan P HattAO Research Institute Davos, 7270 Davos Platz, Switzerland.
Sylvie WirthAO Research Institute Davos, 7270 Davos Platz, Switzerland.
Aapo RistaniemiAO Research Institute Davos, 7270 Davos Platz, Switzerland.
Daniel J CiricAO Research Institute Davos, 7270 Davos Platz, Switzerland.
Keith ThompsonAO Research Institute Davos, 7270 Davos Platz, Switzerland.ORCID https://orcid.org/0000-0002-9167-5147
David EglinAO Research Institute Davos, 7270 Davos Platz, Switzerland.
Martin J StoddartAO Research Institute Davos, 7270 Davos Platz, Switzerland.ORCID https://orcid.org/0000-0002-9538-1517
Angela R ArmientoAO Research Institute Davos, 7270 Davos Platz, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 3D printing process of fused deposition modelling is an attractive fabrication approach to create tissue-engineered bone substitutes to regenerate large mandibular bone defects, but often lacks desired surface porosity for enhanced protein adsorption and cell adhesion. Solvent-based printing leads to the spontaneous formation of micropores on the scaffold's surface upon solvent removal, without the need for further post processing. Our aim is to create and characterize porous scaffolds using a new formulation composed of mechanically stable poly(lactic-co-glycol acid) and osteoconductive β-tricalcium phosphate with and without the addition of elastic thermoplastic polyurethane prepared by solvent-based 3D-printing technique. Large-scale regenerative scaffolds can be 3D-printed with adequate fidelity and show porosity at multiple levels analysed via micro-computer tomography, scanning electron microscopy and N

Indexed as

mesenchymal stromal cellsosteogenesisporosityregenerative scaffoldsolvent-based printing

Identifiers

PMID37936893
PMCPMC10627288

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.