Evidence map›Paper›PMID 37936471›Full record

ArticleCurrent organic synthesis2024

Synthesis, DPPH Radical Scavenging, Cytotoxic Activity, and Apoptosis Induction Efficacy of Novel Thiazoles and Bis-thiazoles.

Amr Negm, Yasair S Al-Faiyz, Sayed M Riyadh, Abdelwahed R Sayed

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Article in Current organic synthesis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amr NegmDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Yasair S Al-FaiyzDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Sayed M RiyadhDepartment of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Abdelwahed R SayedDepartment of Chemistry, Faculty of Science, Beni-Suef University, Beni-suef, 62514, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeterocyclic materials-containing thiazoles exhibited incredible importance in pharmaceutical chemistry and drug design due to their extensive biological properties.

methodsSynthesis of thiazoles and bis-thiazoles from the reaction of 2-((6-Nitrobenzo[ d][1,3]dioxol-5-yl)methylene)hydrazine-1-carbothioamide with hydrazonoyl chlorides in dioxane and in the existence of triethylamine as basic catalyst. The antioxidant,

resultsIn this work, novel series of 5-methyl-2-(2-(-(6-nitrobenzo[d][1,3]dioxol-5-yl)methylene) hydrazinyl)-4-(aryldiazenyl)thiazoles (4a-f) were prepared

conclusionSynthesis, DPPH Radical Scavenging, Cytotoxic activity, and Apoptosis Induction Efficacy based on Novel Thiazoles and Bis-thiazoles.

Indexed as

Antineoplastic AgentsApoptosisCell ProliferationThiazolesAntioxidantsBiphenyl CompoundsCell Line, TumorDrug Screening Assays, AntitumorFree Radical ScavengersHumansMolecular StructurePicratesStructure-Activity Relationship1,1-diphenyl-2-picrylhydrazylAntineoplastic AgentsAntioxidantsBiphenyl CompoundsFree Radical ScavengersPicratesThiazolesanti-cancerantioxidantanti-proliferative agentsapoptosis.Hydrazonoylthiazole

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.