ArticleEuropean heart journal2023
Disparities in donor heart acceptance between the USA and Europe: clinical implications.
Article in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 38 citations in OpenAlex.
- Acceptance of Organs From Deceased Donors: Results of a Global Survey.Transplantation direct · 2026Article
- Waitlist mortality and recovery among pediatric heart transplant candidates in Germany: A nationwide registry analysis.JHLT open · 2026Article
- Extended Criteria Donor Use in Heart Transplantation: A Promising Strategy to Expand the Donor Pool.Journal of clinical medicine · 2026Article
- From innovation to implementation: expanding global access to mechanical circulatory support and heart transplantation.Frontiers in cardiovascular medicine · 2026Review
- Moving Beyond the Perfect Donor: An Interdisciplinary Approach to Optimizing Donor Utilization.JACC. Advances · 2025Article
- Scientific advances in the assessment, modification, and generation of transplantable organs for patients with end-stage organ diseases.Lancet (London, England) · 2025Review
- Reasons for donor heart offer refusal in the United States: Results from 14,132 transplant clinician surveys in the Donor Heart Study.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Observational
- Donor Selection for Heart Transplantation in 2025.JACC. Heart failure · 2025Review
- A critical evaluation of donor heart offer acceptance in the United Kingdom.Annals of cardiothoracic surgery · 2025Article
- Primary Graft Dysfunction after Heart Transplantation: Current Evidence and Implications for Clinical Practice.Current cardiology reports · 2025Review
- Just a number? Donor age and (lack of) associated reasons for heart offer refusal.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Article
- Prediction of Donor Heart Acceptance for Transplant and Its Clinical Implications: Results From The Donor Heart Study.Circulation. Heart failure · 2024Review
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Authors and funding
17 authors at 13 institutions in 8 countries.
Funding
Abstract
BACKGROUND AND
aimsGiven limited evidence and lack of consensus on donor acceptance for heart transplant (HT), selection practices vary widely across HT centres in the USA. Similar variation likely exists on a broader scale-across countries and HT systems-but remains largely unexplored. This study characterized differences in heart donor populations and selection practices between the USA and Eurotransplant-a consortium of eight European countries-and their implications for system-wide outcomes.
methodsCharacteristics of adult reported heart donors and their utilization (the percentage of reported donors accepted for HT) were compared between Eurotransplant (n = 8714) and the USA (n = 60 882) from 2010 to 2020. Predictors of donor acceptance were identified using multivariable logistic regression. Additional analyses estimated the impact of achieving Eurotransplant-level utilization in the USA amongst donors of matched quality, using probability of acceptance as a marker of quality.
resultsEurotransplant reported donors were older with more cardiovascular risk factors but with higher utilization than in the USA (70% vs. 44%). Donor age, smoking history, and diabetes mellitus predicted non-acceptance in the USA and, by a lesser magnitude, in Eurotransplant; donor obesity and hypertension predicted non-acceptance in the USA only. Achieving Eurotransplant-level utilization amongst the top 30%-50% of donors (by quality) would produce an additional 506-930 US HTs annually.
conclusionsEurotransplant countries exhibit more liberal donor heart acceptance practices than the USA. Adopting similar acceptance practices could help alleviate the scarcity of donor hearts and reduce waitlist morbidity in the USA.
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