ArticleBMC medicine2023
Malnutrition-related mortality trends in older adults in the United States from 1999 to 2020.
Article in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Investigating demographic and geographic disparities in malnutrition and gastrointestinal cancer mortality among older adults in the United States: A comprehensive longitudinal Centers for Disease Control and Prevention WONDER analysis 1999-2020.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Decline and Resurgence of Cardiovascular-Kidney-Metabolic Syndrome-Related Deaths Involving Malnutrition in the United States, 1999 to 2023.Journal of the American Heart Association · 2026Article
- Trends and widening inequities in cardiovascular-kidney-metabolic involvement in cardiovascular mortality: A national spatiotemporal analysis, 2014-2023.Clinical medicine (London, England) · 2026Article
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- Trends and Demographics of Hepatorenal Syndrome-Related Mortality in the U.S., 1999-2024: A CDC WONDER Analysis.Diseases (Basel, Switzerland) · 2026Article
- Trends, underlying-cause structure, and penetration of end-stage kidney disease involvement in U.S. mortality, 1999-2023: a multiple-cause-of-death analysis.Frontiers in public health · 2026Article
- Trends and disparities in neoplasm-related mortality with death-certificate-documented protein-energy malnutrition in the United States, 1999-2024: a CDC WONDER multiple cause of death study.Frontiers in nutrition · 2026Article
- National trends and county-level geographic disparities in mortality from operationally defined cardiovascular-kidney-metabolic stages 4 and 4b in the United States.Frontiers in cardiovascular medicine · 2026Article
- Associations of Nutritional Health Risk With Cognitive Function in Older Korean Adults: The Mediating Roles of Lower Body Strength and Depression.Geriatrics & gerontology international · 2025Article
- Rising Deaths due to Malnutrition and Growing Disparities in the U.S.: A 24-Year Trend Analysis From 1999 and 2023.Food science & nutrition · 2025Article
- Malnutrition Mortality Among Older Adults by County and Race and/or Ethnicity in the United States, 2000-2019.Journal of the American Geriatrics Society · 2025Article
- The Overlooked Threat of Malnutrition: A Point Prevalence Study Based on NRS-2002 Screening in a Tertiary Care Hospital.Journal of clinical medicine · 2025Article
- Development of a New Malnutrition Screening Tool for Patients: Human Key Tool of Nutrition.American journal of medicine open · 2025Article
- Demographic and regional trends in systemic and cardiovascular amyloidosis-related mortality among older adults in the United States from 1999 to 2020.Internal and emergency medicine · 2025Observational
- Iron deficiency anemia-related mortality trends in US older subjects, 1999 to 2019.Aging clinical and experimental research · 2025Article
- Correlation between controlling nutritional status score and mortality risk in older Japanese adults diagnosed with dysphagia: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Global patterns of change in the burden of malnutrition in older adults from 1990 to 2021 and the forecast for the next 25 years.Frontiers in nutrition · 2025Article
- Association between Mild Overweight and Survival: A Study of an Exceptionally Long-Lived Population in the Sardinian Blue Zone.Journal of clinical medicine · 2024Article
- Advancing the Understanding of Malnutrition in the Elderly Population: Current Insights and Future Directions.Nutrients · 2024Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition mortality in older adults is underrepresented in scientific literature. This obscures any recent changes and hinders needed social change. This study aims to assess malnutrition mortality trends in older adults (≥ 65 years old) from 1999 to 2020 in the United States (U.S.).
methodsMortality data from the Centers for Disease Control and Prevention's (CDC) Wide-Ranging Online Data for Epidemiology Research (WONDER) database were extracted. The ICD-10 Codes E40 - E46 were used to identify malnutrition deaths. Crude mortality rates (CMR) and age-adjusted mortality rates (AAMR) were extracted by gender, age, race, census region, and urban-rural classification. Joinpoint regression analysis was used to calculate annual percentage changes (APC) of AAMR by the permutation test and the parametric method was used to calculate 95% confidence intervals. Average Annual Percentage Changes (AAPC) were calculated as the weighted average of APCs.
resultsBetween 1999 and 2020, 93,244 older adults died from malnutrition. Malnutrition AAMR increased from 10.7 per 100,000 in 1999 to 25.0 per 100,000 in 2020. The mortality trend declined from 1999 to 2006 (APC = -8.8; 95% CI: -10.0, -7.5), plateaued till 2013, then began to rise from 2013 to 2020 with an APC of 22.4 (95% CI: 21.3, 23.5) and an overall AAPC of 3.9 (95% CI: 3.1, 4.7). Persons ≥ 85 years of age, females, Non-Hispanic Whites, residents of the West region of the U.S., and urban areas had the highest AAPCs in their respective groups.
conclusionDespite some initial decrements in malnutrition mortality among older adults in the U.S., the uptrend from 2013 to 2020 nullified all established progress. The end result is that malnutrition mortality rates represent a historical high. The burden of the mortality uptrends disproportionately affected certain demographics, namely persons ≥ 85 years of age, females, Non-Hispanic Whites, those living in the West region of the U.S., and urban areas. Effective interventions are strongly needed. Such interventions should aim to ensure food security and early detection and remedy of malnutrition among older adults through stronger government-funded programs and social support systems, increased funding for nursing homes, and more cohesive patient-centered medical care.
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