Evidence map›Paper›PMID 37936133›Full record

SynthesisBMC urology2023

Super pulsed thulium fiber laser outcomes in retrograde intrarenal surgery for ureteral and renal stones: a systematic review and meta-analysis.

Nazal A Almasoud, Omar Safar, Adel Elatreisy, Saad Thamer Alshahrani, Saud Bin Libdah, Sulaiman M Alkhaldi, Nezar F Alsoliman, Abdulrahman M Alderaan, Ibrahim Abdel-Al, Tamer A Abouelgreed and 2 more

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07639385 (Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07639385 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm

TypeinterventionalSponsorBir HospitalRan2026 to 2027Enrolled86ConditionsThulium Fiber Laser, Fans, Lithotripsy, Laser, Renal StoneArmsDusting, Fragmentation
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nazal A AlmasoudUrology Department, Prince Mutaib Bin Abdulaziz Hospital, Sakaka, Aljouf province, Saudi Arabia.
Omar SafarUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia. omar2725@hotmail.com.ORCID http://orcid.org/0000-0001-8306-690X
Adel ElatreisyUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia.
Saad Thamer AlshahraniUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia.
Saud Bin LibdahUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia.
Sulaiman M AlkhaldiUrology Department, Prince Mutaib Bin Abdulaziz Hospital, Sakaka, Aljouf province, Saudi Arabia.
Nezar F AlsolimanUrology Department, Prince Mutaib Bin Abdulaziz Hospital, Sakaka, Aljouf province, Saudi Arabia.
Abdulrahman M AlderaanUrology Department, Prince Mutaib Bin Abdulaziz Hospital, Sakaka, Aljouf province, Saudi Arabia.
Ibrahim Abdel-AlUrology Department, Faculty of Medicine, Al-Azher University, Assiut Branch, Assiut, Egypt.
Tamer A AbouelgreedUrology Department, Faculty of Medicine, Al-Azher University, Cairo, Egypt.
Mohammed AlabeediUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia.
Abdulrahman Al-AownUrology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Aseer Province, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser lithotripsy using a thulium fiber laser (TFL) has become an effective treatment option for small renal stones with low complication rates. TFL has a higher absorption coefficient, smaller fibers, and better pulse rate capability.

methodsWe conducted a systematic review and meta-analysis to evaluate the published evidence regarding TFL's lithotripsy performance in retrograde intrarenal surgery (RIRS), for which we primarily assessed the outcomes of stone-free rate, operation time, and complications. We searched different databases from inception to April 2023. We assessed the methodological quality and risk of bias using the Cochrane Risk of Bias tool for randomized trials and the ROBINS-I tool for non-randomized studies. We used a random-effects model for meta-analysis and assessed heterogeneity using the I2 statistic.

resultsTwelve published studies evaluated the efficacy of RIRS using a TFL for treating renal and ureteral stones. The meta-analysis revealed a predicted stone-free rate of 89.37% (95% CI: 83.93% to 93.12%), indicating that, on average, approximately 89.37% of patients achieved a stone-free state after treatment. The substantial heterogeneity among the studies was evident, as shown by a Q-value of 33.1174 and a p-value of 0.0003. The I

conclusionThis meta-analysis suggests that RIRS using TFL is an effective and safe treatment option for renal and ureteral stones, with high stone-free and low complication rates. The included studies exhibited a low risk of bias and were of high quality. However, more extensive randomized controlled trials with extended follow-up periods are needed to investigate this technique's efficacy and safety.

Indexed as

Kidney CalculiLithotripsyLithotripsy, LaserUreterUreteral CalculiHumansKidneyLasersThuliumTreatment OutcomeThuliumKidney stoneLaserLithotripsyThulium

Identifiers

PMID37936133
PMCPMC10631031

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.