Evidence map›Paper›PMID 37936115›Full record

ReviewJournal of nanobiotechnology2023

Field effect transistor based wearable biosensors for healthcare monitoring.

Thi Thanh-Ha Nguyen, Cong Minh Nguyen, Minh Anh Huynh, Hoang Huy Vu, Tuan-Khoa Nguyen, Nam-Trung Nguyen

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thi Thanh-Ha NguyenQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.ORCID https://orcid.org/0000-0002-7248-2075
Cong Minh NguyenQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.ORCID https://orcid.org/0000-0003-1839-5111
Minh Anh HuynhQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.ORCID https://orcid.org/0009-0004-6871-4103
Hoang Huy VuQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.ORCID https://orcid.org/0000-0002-4845-6627
Tuan-Khoa NguyenQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia.ORCID https://orcid.org/0000-0003-1271-9576
Nam-Trung NguyenQueensland Micro- and Nanotechnology Centre, Griffith University, Nathan, QLD, 4111, Australia. nam-trung.nguyen@griffith.edu.au.ORCID https://orcid.org/0000-0003-3626-5361

Funding

Australian Research Council DP220100261
6 · The paper itself

Abstract

The rapid advancement of wearable biosensors has revolutionized healthcare monitoring by screening in a non-invasive and continuous manner. Among various sensing techniques, field-effect transistor (FET)-based wearable biosensors attract increasing attention due to their advantages such as label-free detection, fast response, easy operation, and capability of integration. This review explores the innovative developments and applications of FET-based wearable biosensors for healthcare monitoring. Beginning with an introduction to the significance of wearable biosensors, the paper gives an overview of structural and operational principles of FETs, providing insights into their diverse classifications. Next, the paper discusses the fabrication methods, semiconductor surface modification techniques and gate surface functionalization strategies. This background lays the foundation for exploring specific FET-based biosensor designs, including enzyme, antibody and nanobody, aptamer, as well as ion-sensitive membrane sensors. Subsequently, the paper investigates the incorporation of FET-based biosensors in monitoring biomarkers present in physiological fluids such as sweat, tears, saliva, and skin interstitial fluid (ISF). Finally, we address challenges, technical issues, and opportunities related to FET-based biosensor applications. This comprehensive review underscores the transformative potential of FET-based wearable biosensors in healthcare monitoring. By offering a multidimensional perspective on device design, fabrication, functionalization and applications, this paper aims to serve as a valuable resource for researchers in the field of biosensing technology and personalized healthcare.

Indexed as

Biosensing TechniquesWearable Electronic DevicesBiomarkersSalivaSweatBiomarkersbioFETBiosensorField effect transistorInterstitial fluidNon-invasive monitoringSalivaSweatTearWearable device

Identifiers

PMID37936115
PMCPMC10629051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.