Evidence map›Paper›PMID 37936077›Full record

ArticleBMC infectious diseases2023

Delayed diagnosis of Lemierre's syndrome in a patient with severe coronavirus disease 2019: importance of comprehensive oral and neck examination - a case report.

Tomotaka Miura, Hirotsugu Fukuda, Hiroshi Kawada, Tetsuro Kaga, Masayuki Matsuo, Tsutomu Sakai, Shozo Yoshida, Hideshi Okada, Shinji Ogura, Nobuyuki Tetsuka

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tomotaka MiuraAdvanced Critical Care Center, Gifu University Hospital, Gifu, Japan.
Hirotsugu FukudaAdvanced Critical Care Center, Gifu University Hospital, Gifu, Japan.
Hiroshi KawadaDepartment of Radiology, Gifu University, Gifu, Japan.
Tetsuro KagaDepartment of Radiology, Gifu University, Gifu, Japan.
Masayuki MatsuoDepartment of Radiology, Gifu University, Gifu, Japan.
Tsutomu SakaiGastroenterology, Hashima City Hospital, Gifu, Japan.
Shozo YoshidaAdvanced Critical Care Center, Gifu University Hospital, Gifu, Japan.
Hideshi OkadaAdvanced Critical Care Center, Gifu University Hospital, Gifu, Japan.
Shinji OguraAdvanced Critical Care Center, Gifu University Hospital, Gifu, Japan.
Nobuyuki TetsukaDepartment of Infection Control, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu-Shi, Gifu, 501-1194, Japan. tetsuka.nobuyuki.e8@f.gifu-u.ac.jp.
Gifu University · JPGifu University Hospital · JPGifu Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the widespread prevalence of the coronavirus disease 2019 (COVID-19), oral and neck examinations tend to be avoided in patients with suspected or confirmed COVID-19. This might delay the diagnosis of conditions such as Lemierre's syndrome, which involves symptoms resembling COVID-19-related throat manifestations. CASE PRESENTATION: A 24-year-old man without any underlying conditions was diagnosed with COVID-19 7 days before presentation. He was admitted to another hospital 1 day before presentation with severe COVID-19 and suspected bacterial pneumonia; accordingly, he was started on treatment with remdesivir and meropenem. Owing to bacteremic complications, the patient was transferred to our hospital for intensive care. On the sixth day, the patient experienced hemoptysis; further, a computed tomography (CT) scan revealed new pulmonary artery pseudoaneurysms. Successful embolization was performed to achieve hemostasis. In blood cultures conducted at the previous hospital, Fusobacterium nucleatum was isolated, suggesting a cervical origin of the infection. A neck CT scan confirmed a peritonsillar abscess and left internal jugular vein thrombus; accordingly, he was diagnosed with Lemierre's syndrome. The treatment was switched to ampicillin/sulbactam, based on the drug susceptibility results. After 6 weeks of treatment, the patient completely recovered without complications.

conclusionThis case highlights the significance of thorough oral and neck examinations in patients with suspected or diagnosed COVID-19 for the detection of throat and neck symptoms caused by other conditions.

Indexed as

COVID-19Lemierre SyndromeBlood CultureCOVID-19 TestingDelayed DiagnosisHumansMaleNeckYoung AdultCase reportCoronavirus disease 2019Interventional radiologyLemierre’s syndromePulmonary artery pseudoaneurysm

Identifiers

PMID37936077
PMCPMC10629146
OpenAlexW4388455075

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.