Evidence map›Paper›PMID 37935826›Full record

ArticleDiabetologia2024

Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes.

Achyut Ram Vyakaranam, Maryama M Mahamed, Per Hellman, Olof Eriksson, Daniel Espes, Gustaf Christoffersson, Anders Sundin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Achyut Ram VyakaranamDepartment of Surgical Sciences, Section of Radiology & Molecular Imaging, Uppsala University, Uppsala, Sweden. achyutram.vyakaranam@surgsci.uu.se.ORCID 0000-0002-6754-9853
Maryama M MahamedDepartment of Surgical Sciences, Section of Radiology & Molecular Imaging, Uppsala University, Uppsala, Sweden.
Per HellmanDepartment of Surgical Sciences, Section of Radiology & Molecular Imaging, Uppsala University, Uppsala, Sweden.
Olof ErikssonScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Daniel EspesScience for Life Laboratory, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Gustaf ChristofferssonScience for Life Laboratory, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Anders SundinDepartment of Surgical Sciences, Section of Radiology & Molecular Imaging, Uppsala University, Uppsala, Sweden.
Uppsala University · SE

Funding

ALF agreement ASALF agreement PHInsamlingsstiftelsen Diabetes Wellness Network Sverige 2409-PGScience for Life Laboratory DEScience for Life Laboratory Fellowships to GCScience for Life Laboratory OEVetenskapsrådet 2018-02314Vetenskapsrådet 2020-02312Vetenskapsrådet GCVetenskapsrådet OE
6 · The paper itself

Abstract

aims/hypothesisCompromised pancreatic sympathetic innervation has been suggested as a factor involved in both immune-mediated beta cell destruction and endocrine dysregulation of pancreatic islets. To further explore these intriguing findings, new techniques for in vivo assessment of pancreatic innervation are required. This is a retrospective study that aimed to investigate whether the noradrenaline (norepinephrine) analogue

methodsIn 25 individuals with type 2 diabetes and 64 individuals without diabetes, all of whom had previously undergone

resultsGenerally, CONCLUSIONS/

interpretationWe demonstrate the feasibility of using

Indexed as

Diabetes Mellitus, Type 2EphedrineHeartHumansPancreasPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesSympathetic Nervous SystemEphedrine11C-HED11C-hydroxy ephedrineA41DiabetesInnervationPET-CT specific binding index

Identifiers

PMID37935826
PMCPMC10709256
OpenAlexW4388448761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.