Evidence map›Paper›PMID 37935801›Full record

ArticleScientific reports2023

Impact of sex and age on vaccine-related side effects and their progression after booster mRNA COVID-19 vaccine.

Masahiko Mori, Aiko Yokoyama, Ayami Shichida, Kimiko Sasuga, Takafumi Maekawa, Tadayoshi Moriyama

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Masahiko MoriDepartment of Internal Medicine, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan. medicaloffice@kinenhp.or.jp.
Aiko YokoyamaRegional medical cooperation office, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan.
Ayami ShichidaMedical Administration Division, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan.
Kimiko SasugaDepartment of Medical Information, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan.
Takafumi MaekawaDepartment of Surgery, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan.
Tadayoshi MoriyamaDepartment of Neurosurgery, Sasebo Memorial Hospital, Sasebo, Nagasaki, 858-0922, Japan.
Sasebo City General Hospital · JPFukuoka Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mRNA COVID-19 vaccination, side effects after the first and second dose have been well reported. However, studies about side effects after booster vaccine are sparse. 272 healthcare workers who received the third mRNA COVID-19 vaccine were recruited, and impact of sex, age, and symptoms on the side effect progression was statistically analyzed. Females and younger adults had a higher frequencies of general fatigue, headache, joint pain, chills and axillary pain compared to males and elderly adults, respectively. In longitudinal analysis, prolonged time to recovery from side effects was found among females and younger adults. Finally, between the third and second dose vaccinations, 52% of subjects had a longer duration of side effects following the third vaccine compared to the second, and joint pain was the culprit symptom related to the prolonged duration of side effects. Following the second vaccine dose, 25% of subjects had a longer duration of side effects and asthma and ear fullness, which exacerbated the underlying allergic condition, and COVID arm symptom were the culprit symptoms. These highlight the impact of sex, age, and culprit symptoms on the progress of side effects following the booster mRNA COVID-19 vaccine.

Indexed as

COVID-19Drug-Related Side Effects and Adverse ReactionsAdultAgedAge FactorsArthralgiaCOVID-19 VaccinesFatigueFemaleHumansImmunization, SecondaryMaleRNA, MessengerSex FactorsVaccinesCOVID-19 VaccinesRNA, MessengerVaccines

Identifiers

PMID37935801
PMCPMC10630308
OpenAlexW4388465519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.