ArticleScientific reports2023
Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- High hepatitis E virus prevalence in pig slurry samples from the north-western region of Germany.One health (Amsterdam, Netherlands) · 2026Article
- Environmental considerations in hepatitis E virus transmission: Is there a missing link?World journal of hepatology · 2026Review
- Serological and molecular survey of hepatitis E virus in pets in shaanxi, China.BMC veterinary research · 2025Article
- Detection of anti-HEV antibodies but no molecular positivity in dogs in the Campania region, southern Italy.One health (Amsterdam, Netherlands) · 2024Article
- Serological survey on Hepatitis E virus in Namibian dogs, cats, horses, and donkeys.Frontiers in veterinary science · 2024Article
- Severe hepatitis E virus genotype 3b in a patient with alcohol‑associated liver disease: A case report.Medicine internationalArticle
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as possible sources of HEV transmission in Germany still needs to be defined. A monitoring study was therefore carried out on dogs, cats, and horses from Germany. In total 365 serum samples from pets (124 dogs, 119 cats, and 122 horses) were tested for HEV by PCR and for anti-HEV antibodies by a commercial ELISA. The HEV seroprevalence determined by the sero-assay varied significantly between dogs (10%), cats (6%), and horses (2%). Liver injury-related enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) showed no differences between HEV-positive or negative animals. None of the pet serum samples tested positive for PCR. This serological study suggests that dogs and cats are significantly exposed to HEV in Germany, while horses are of minor relevance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.