Evidence map›Paper›PMID 37935525›Full record

ArticleRespiratory care2024

Home Noninvasive Ventilation in Myasthenia Gravis.

Jesús Sancho, Santos Ferrer, Antonio Quezada, Elia Gimenez, Jaime Signes-Costa

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jesús SanchoDrs Sancho, Ferrer, Quezada, and Gimenez are affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; and Institute of Health Research INCLIVA, Valencia, Spain. Dr signes-costa is affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; Institute of Health Research INCLIVA, Valencia, Spain; and University of Valencia, Valencia, Spain. jesus.sancho@uv.es.
Santos FerrerDrs Sancho, Ferrer, Quezada, and Gimenez are affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; and Institute of Health Research INCLIVA, Valencia, Spain. Dr signes-costa is affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; Institute of Health Research INCLIVA, Valencia, Spain; and University of Valencia, Valencia, Spain.
Antonio QuezadaDrs Sancho, Ferrer, Quezada, and Gimenez are affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; and Institute of Health Research INCLIVA, Valencia, Spain. Dr signes-costa is affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; Institute of Health Research INCLIVA, Valencia, Spain; and University of Valencia, Valencia, Spain.
Elia GimenezDrs Sancho, Ferrer, Quezada, and Gimenez are affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; and Institute of Health Research INCLIVA, Valencia, Spain. Dr signes-costa is affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; Institute of Health Research INCLIVA, Valencia, Spain; and University of Valencia, Valencia, Spain.
Jaime Signes-CostaDrs Sancho, Ferrer, Quezada, and Gimenez are affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; and Institute of Health Research INCLIVA, Valencia, Spain. Dr signes-costa is affiliated with Respiratory Medicine Department, Hospital Clínico Universitario, Valencia, Spain; Institute of Health Research INCLIVA, Valencia, Spain; and University of Valencia, Valencia, Spain.
Universitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNoninvasive ventilation (NIV) plays an important role in avoiding endotracheal intubation during myasthenic crisis, yet there are few published data concerning long-term home NIV in stable out-patients with myasthenia gravis (MG). The aim of this study was to describe the prevalence of NIV in a cohort of subjects with stable MG and to analyze contributing factors that could predict the need of NIV.

methodsWe performed a cross-sectional study that included subjects diagnosed with MG managed in the respiratory care unit over the previous year. Subjects underwent clinical analysis including demographic, clinical, and functional respiratory data.

resultsOf the 50 subjects included, 35 (70%) were positive for nicotinic acetylcholine receptor antibodies, and 68% had a diagnosis of generalized MG. Bulbar symptoms developed in 16 (32%), and 10 (20%) subjects needed long-term home NIV. The only variable predicting the need for long-term NIV was MG severity measured with Myasthenia Gravis Foundation of America (MGFA), mainly grades IIB (odds ratio 0.14 [95% CI 0.02-0.85],

conclusionsHome NIV was needed in a substantial percentage of medically stable subjects with MG, mainly in those with generalized type and with oropharyngeal and/or respiratory muscle involvement (MGFA grades IIB and IIIB).

Indexed as

Myasthenia GravisNoninvasive VentilationRespiratory InsufficiencyCross-Sectional StudiesHumansIntubation, IntratrachealOropharynxRetrospective Studiesmyasthenia gravisnoninvasive ventilationrespiratory failure

Identifiers

PMID37935525
PMCPMC10984589
OpenAlexW4388445800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.