Evidence map›Paper›PMID 37935464›Full record

ArticleLife science alliance2024

Spt5 interacts genetically with Myc and is limiting for brain tumor growth in

Julia Hofstetter, Ayoola Ogunleye, André Kutschke, Lisa Marie Buchholz, Elmar Wolf, Thomas Raabe, Peter Gallant

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. DNA repair in tumor radioresistance: insights from fruit flies genetics.Cellular oncology (Dordrecht, Netherlands) · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Julia HofstetterCancer Systems Biology Group, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.ORCID https://orcid.org/0000-0003-4496-2394
Ayoola OgunleyeDepartment of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.ORCID https://orcid.org/0000-0001-8533-4875
André KutschkeCancer Systems Biology Group, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Lisa Marie BuchholzDepartment of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Elmar WolfCancer Systems Biology Group, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany elmar.wolf@uni-wuerzburg.de.ORCID https://orcid.org/0000-0002-5299-6335
Thomas RaabeMolecular Genetics, Biocenter, Am Hubland, University of Würzburg, Würzburg, Germany thomas.raabe@uni-wuerzburg.de.ORCID https://orcid.org/0000-0001-9734-4464
Peter GallantDepartment of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany peter.gallant@uni-wuerzburg.de.ORCID https://orcid.org/0000-0002-8270-5738
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor SPT5 physically interacts with MYC oncoproteins and is essential for efficient transcriptional activation of MYC targets in cultured cells. Here, we use

Indexed as

Brain NeoplasmsDrosophilaAnimalsBrainChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDrosophila ProteinsHumansNuclear ProteinsTranscriptional Elongation FactorsTranscription FactorsChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDrosophila ProteinsMyc protein, DrosophilaNuclear ProteinsSPT5 transcriptional elongation factorTranscriptional Elongation FactorsTranscription Factors

Identifiers

PMID37935464
PMCPMC10629571
OpenAlexW4388463605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.