Evidence map›Paper›PMID 37935439›Full record

ArticleJournal of experimental botany2024

The conservation of allelic DNA methylation and its relationship with imprinting in maize.

Xiaomei Dong, Haishan Luo, Jiabin Yao, Qingfeng Guo, Shuai Yu, Yanye Ruan, Fenghai Li, Weiwei Jin, Dexuan Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of experimental botany, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaomei DongCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Haishan LuoCollege of Agronomy, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Jiabin YaoCollege of Agronomy, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Qingfeng GuoCollege of Agronomy, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Shuai YuCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Yanye RuanCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Fenghai LiCollege of Agronomy, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.
Weiwei JinState Key Laboratory of Plant Physiology and Biochemistry, National Maize Improvement Center, Key Laboratory of Crop Heterosis and Utilization, the Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-9320-9628
Dexuan MengCollege of Agronomy, Shenyang Agricultural University, Shenyang 110866, Liaoning, China.

Funding

National Natural Science Foundation of China 31801368Natural Science Foundation of Liaoning Province 2022-NLTS-19-02
6 · The paper itself

Abstract

Genomic imprinting refers to allele-specific expression of genes depending on parental origin, and it is regulated by epigenetic modifications. Intraspecific allelic variation for imprinting has been detected; however, the intraspecific genome-wide allelic epigenetic variation in maize and its correlation with imprinting variants remain unclear. Here, three reciprocal hybrids were generated by crossing Zea mays inbred lines CAU5, B73, and Mo17 in order to examine the intraspecific conservation of the imprinted genes in the kernel. The majority of imprinted genes exhibited intraspecific conservation, and these genes also exhibited interspecific conservation (rice, sorghum, and Arabidopsis) and were enriched in some specific pathways. By comparing intraspecific allelic DNA methylation in the endosperm, we found that nearly 15% of DNA methylation existed as allelic variants. The intraspecific whole-genome correlation between DNA methylation and imprinted genes indicated that DNA methylation variants play an important role in imprinting variants. Disruption of two conserved imprinted genes using CRISPR/Cas9 editing resulted in a smaller kernel phenotype. Our results shed light on the intraspecific correlation of DNA methylation variants and variation for imprinting in maize, and show that imprinted genes play an important role in kernel development.

Indexed as

DNA MethylationZea maysAllelesEndospermGene Expression Regulation, PlantGenomic ImprintingDNA methylationimprinted genesinterspecific conservationintraspecific conservationkernel developmentmaizeZea mays

Identifiers

PMID37935439
PMCPMC10901201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.