Evidence map›Paper›PMID 37935270›Full record

ArticleFitoterapia2024

LC-MS identification, isolation, and structural elucidation of anti-HIV macrocyclic daphnane orthoesters from Edgeworthia chrysantha.

Kouharu Otsuki, Tsubasa Kobayashi, Kazuki Nakamura, Takashi Kikuchi, Li Huang, Chin-Ho Chen, Kazuo Koike, Wei Li

Abstract read
In one paragraph

Article in Fitoterapia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kouharu OtsukiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan. Electronic address: Kouharu.otsuki@phar.toho-u.ac.jp.
Tsubasa KobayashiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Kazuki NakamuraFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Takashi KikuchiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Li HuangSurgical Sciences, Department of Surgery, Duke University Medical Center, Durham, NC 27710, United States.
Chin-Ho ChenSurgical Sciences, Department of Surgery, Duke University Medical Center, Durham, NC 27710, United States.
Kazuo KoikeFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Wei LiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan. Electronic address: liwei@phar.toho-u.ac.jp.

Funding

New Non-Nuceleotide Reverse Transcriptase Inhibitors for Drug Resistant HIV StrainsR01AI165473 · NIAID · DUKE UNIVERSITY · PI CHEN, CHIN-HO · 2021 to 2023
$1.6M
NIAID NIH HHS R01 AI165473
6 · The paper itself

Abstract

The occurrence of macrocyclic daphnane orthoesters (MDOs) with a 1-alkyl group originating from a C

Indexed as

DiterpenesThymelaeaceaeChromatography, LiquidLiquid Chromatography-Mass SpectrometryMolecular StructureTandem Mass SpectrometryDiterpenesmezereinAnti-HIVDaphnaneEdgeworthia chrysanthaLC-MSThymelaeaceae

Identifiers

PMID37935270
PMCPMC10842090

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.