Evidence map›Paper›PMID 37934820›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Essential requirement for IER3IP1 in B cell development.

Xue Zhong, James J Moresco, Katie Keller, Danielle Renee Lazaro, Claire Ely, Eva Marie Y Moresco, Bruce Beutler, Jin Huk Choi

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Essential requirement for IER3IP1 in B cell development.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xue ZhongCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.
James J MorescoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.ORCID 0000-0003-1178-1642
Katie KellerCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.
Danielle Renee LazaroCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.
Claire ElyCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.
Eva Marie Y MorescoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.ORCID 0000-0002-2049-7291
Bruce BeutlerCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.ORCID 0000-0002-3639-246X
Jin Huk ChoiCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505.ORCID 0000-0003-2483-4379
The University of Texas Southwestern Medical Center · US

Funding

Automated Forward Genetic Analysis of Adaptive ImmunityR01AI125581 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BRUCE A BEUTLER · 2016 to 2026
$19.5M
NIAID NIH HHS R01 AI125581
6 · The paper itself

Abstract

In a forward genetic screen of mice with

Indexed as

Diabetes MellitusEpilepsyMicrocephalyAnimalsHumansMembrane ProteinsMiceMutationUnfolded Protein ResponseMembrane ProteinsB cellsENUIER3IP1TMEM167Aunfolded protein response

Identifiers

PMID37934820
PMCPMC10655558
OpenAlexW4388451294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.