Evidence map›Paper›PMID 37934733›Full record

Observational studyRevista medica del Instituto Mexicano del Seguro Social2023

[Factors associated with benzodiazepines dependence in insomnia patients].

Angélica Maravillas-Estrada, Ivonne Analí Roy-García, Rodolfo Rivas-Ruiz, Eduardo Vilchis-Chaparro

Abstract readEnglish AbstractObservational Study
In one paragraph

Observational study in Revista medica del Instituto Mexicano del Seguro Social, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Angélica Maravillas-EstradaInstituto Mexicano del Seguro Social, Hospital General de Zona con Medicina Familiar No. 8 "Dr Gilberto Flores Izquierdo", Departamento de Enseñanza. Ciudad de México, México.ORCID 0000-0003-4183-3570
Ivonne Analí Roy-GarcíaInstituto Mexicano del Seguro Social, Hospital General de Zona con Medicina Familiar No. 8 "Dr Gilberto Flores Izquierdo", Departamento de Enseñanza. Ciudad de México, México.ORCID 0000-0002-1859-3866
Rodolfo Rivas-RuizInstituto Mexicano del Seguro Social, Coordinación de Investigación en Salud, Centro de Adiestramiento en Investigación Clínica. Ciudad de México, México.ORCID 0000-0002-5967-7222
Eduardo Vilchis-ChaparroInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Centro de Investigación Educativa y Formación Docente. Ciudad de México, México.ORCID 0000-0002-4019-9742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of benzodiazepines as a treatment for insomnia can have side effects such as impaired coordination causing falls in adults and even dependence. Objective: To assess the factors associated with dependence on benzodiazepines in patients with insomnia. Methods: Observational, cross-sectional, prospective, and analytical study, at the first level of care. Patients older than 18 years with a diagnosis of insomnia and a benzodiazepine prescription were selected. The dependency was measured with the International Neuropsychiatric Interview. Results: 107 patients were included. Median age 67 years, predominantly female (72%), 74% attended secondary school or more, 71% had more than 3 years of diagnosis, 84% used clonazepam. The 54% presented dependency. In the bivariate analysis, schooling RM 0.392 (95%CI: 0.15-0.96) p = 0.038, moderate and severe clinical insomnia RM 3.618 (95%CI: 1.44-9.08) p = 0.005 and more than 3 years of diagnosis RM 2.428 (95%CI: 1.03-5.71) p = 0.040. In the multivariate model, schooling (p = 0.084), years of diagnosis (p = 0.062) and frequency of consumption (p = 0.065) obtained an R2 of 0.13. Conclusions: Primary schooling showed a lower risk of presenting dependence on benzodiazepines. The risk was increased in those with more than 3 years of diagnosis, and in those with moderate and severe insomnia.

Indexed as

Sleep Initiation and Maintenance DisordersSubstance-Related DisordersAdultAgedBenzodiazepinesCross-Sectional StudiesFemaleHumansHypnotics and SedativesMaleProspective StudiesBenzodiazepinesHypnotics and SedativesBenzodiazepinasBenzodiazepinesEstudio ObservacionalObservational StudySleep Initiation and Maintenance DisordersSubstance-Related DisordersTrastornos del Inicio y del Mantenimiento del SueñoTrastornos Relacionados con Sustancias

Identifiers

PMID37934733
PMCPMC10732695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.