Evidence map›Paper›PMID 37934672›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease.

Joselyn Rojas-Quintero, Scott A Ochsner, Felicia New, Prajan Divakar, Chen Xi Yang, Tianshi David Wu, Jerid Robinson, Darshan Shimoga Chandrashekar, Nicholas E Banovich, Ivan O Rosas and 7 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 35 citations in OpenAlex.

  1. Preclinical models of COPD: a state of the art review.The European respiratory journal · 2026
    Review
  2. Integrated Bioinformatics and Experimental Validation to Identify Shared Sialylation-Related Signatures in Emphysematous and Fibrotic Lung Disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Multi-omics to study chronic respiratory diseases and viral infections.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  17. Review
  18. COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications.International journal of chronic obstructive pulmonary disease · 2026
    Review
  19. From Web to Collapse: Small Airway Disease Trajectory in Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Joselyn Rojas-QuinteroPulmonary Division, Department of Medicine, and.
Scott A OchsnerDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Felicia NewSpatial Data Analysis Services, Nanostring Biotechnologies, Seattle, Washington.
Prajan DivakarSpatial Data Analysis Services, Nanostring Biotechnologies, Seattle, Washington.
Chen Xi YangCenter for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.
Tianshi David WuPulmonary Division, Department of Medicine, and.
Jerid RobinsonField Application Scientists, Nanostring Biotechnologies, Seattle, Washington.
Darshan Shimoga ChandrashekarPathology, Division of Genomic Diagnostics & Bioinformatics, and.
Nicholas E BanovichTranslational Genomics Research Institute, Phoenix, Arizona.
Ivan O RosasPulmonary Division, Department of Medicine, and.
Maor SaulerPulmonary and Critical Care Medicine, Yale University, New Haven, Connecticut.
Farrah KheradmandPulmonary Division, Department of Medicine, and.
Amit GaggarPulmonary and Critical Care Medicine, and.
Camilla MargaroliPathology - Division of Cellular and Molecular Pathology, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-3952-0778
Raul San Jose EsteparApplied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-3677-1996
Neil J McKennaSpatial Data Analysis Services, Nanostring Biotechnologies, Seattle, Washington.
Francesca PolverinoPulmonary Division, Department of Medicine, and.ORCID 0000-0001-9686-5698
Baylor College of Medicine · USNanostring Technologies (United States) · USUniversity of Alabama at Birmingham · USBrigham and Women's Hospital · USMichael E. DeBakey VA Medical Center · USTranslational Genomics Research Institute · USUniversity of British Columbia · CAYale University · US

Funding

B cell-adaptive Immune Profile in Emphysema-predominant COPDR01HL149744 · NHLBI · UNIVERSITY OF ARIZONA · PI POLVERINO, FRANCESCA · 2020 to 2024
$3.4M
Role of MIF and CD74 in the pathogenesis of emphysemaR01HL155948 · NHLBI · YALE UNIVERSITY · PI BUCALA, RICHARD J, SAULER, MAOR · 2021 to 2025
$3.4M
Prognostic Markers of Emphysema ProgressionR01HL149877 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2020 to 2023
$2.8M
NHLBI NIH HHS HL149744NHLBI NIH HHS R01 HL149744NHLBI NIH HHS R01 HL149877NHLBI NIH HHS R01 HL155948
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EmphysemaLymphadenopathyPulmonary Disease, Chronic ObstructivePulmonary EmphysemaGene Expression ProfilingHumansProteomicsautoimmunitycentrilobular emphysemalymphoid folliclesmetabolic reprogrammingswitch-class recombination

Identifiers

PMID37934672
PMCPMC10870877
OpenAlexW4388453177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.