Evidence map›Paper›PMID 37934344›Full record

ArticleInsights into imaging2023

Artificial CT images can enhance variation of case images in diagnostic radiology skills training.

Elfi Inez Saïda Hofmeijer, Sheng-Chih Wu, Rozemarijn Vliegenthart, Cornelis Herman Slump, Ferdi van der Heijden, Can Ozan Tan

Abstract read
In one paragraph

Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elfi Inez Saïda HofmeijerRobotics and Mechatronics, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, Enschede, The Netherlands. e.i.s.hofmeijer@utwente.nl.ORCID http://orcid.org/0000-0002-4492-311X
Sheng-Chih WuRobotics and Mechatronics, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, Enschede, The Netherlands.
Rozemarijn VliegenthartDept of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Cornelis Herman SlumpRobotics and Mechatronics, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, Enschede, The Netherlands.
Ferdi van der HeijdenRobotics and Mechatronics, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, Enschede, The Netherlands.
Can Ozan TanRobotics and Mechatronics, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, Enschede, The Netherlands.

Funding

ZonMw 10-10400-98-008
6 · The paper itself

Abstract

objectivesWe sought to investigate if artificial medical images can blend with original ones and whether they adhere to the variable anatomical constraints provided.

methodsArtificial images were generated with a generative model trained on publicly available standard and low-dose chest CT images (805 scans; 39,803 2D images), of which 17% contained evidence of pathological formations (lung nodules). The test set (90 scans; 5121 2D images) was used to assess if artificial images (512 × 512 primary and control image sets) blended in with original images, using both quantitative metrics and expert opinion. We further assessed if pathology characteristics in the artificial images can be manipulated.

resultsPrimary and control artificial images attained an average objective similarity of 0.78 ± 0.04 (ranging from 0 [entirely dissimilar] to 1[identical]) and 0.76 ± 0.06, respectively. Five radiologists with experience in chest and thoracic imaging provided a subjective measure of image quality; they rated artificial images as 3.13 ± 0.46 (range of 1 [unrealistic] to 4 [almost indistinguishable to the original image]), close to their rating of the original images (3.73 ± 0.31). Radiologists clearly distinguished images in the control sets (2.32 ± 0.48 and 1.07 ± 0.19). In almost a quarter of the scenarios, they were not able to distinguish primary artificial images from the original ones.

conclusionArtificial images can be generated in a way such that they blend in with original images and adhere to anatomical constraints, which can be manipulated to augment the variability of cases. CRITICAL RELEVANCE STATEMENT: Artificial medical images can be used to enhance the availability and variety of medical training images by creating new but comparable images that can blend in with original images. KEY POINTS: • Artificial images, similar to original ones, can be created using generative networks. • Pathological features of artificial images can be adjusted through guiding the network. • Artificial images proved viable to augment the depth and broadening of diagnostic training.

Indexed as

Artificial imageArtificial intelligenceMedical image educationPersonalized educationRadiology

Identifiers

PMID37934344
PMCPMC10630276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.