Evidence map›Paper›PMID 37934298›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

"Take the tablet or don't take the tablet?"-A qualitative study of patients' experiences of self-administering anti-cancer medications related to adherence and managing side effects.

Thu Ha Dang, Clare O'Callaghan, Marliese Alexander, Kate Burbury, Prem Prakash Jayaraman, Nilmini Wickramasinghe, Penelope Schofield

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Patient symptoms, confidence, and adherence during the first 8 weeks of targeted oral anticancer agent treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
  6. Perceptions of oncology healthcare professional providing care to older adults prescribed oral anticancer medications in the United States: A qualitative study.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thu Ha DangDepartment of Psychological Sciences, School of Health Sciences, Swinburne University of Technology, Melbourne, VIC, Australia. thuhadang@swin.edu.au.ORCID http://orcid.org/0000-0001-9105-6920
Clare O'CallaghanCaritas Christi and Psychosocial Cancer Care, St Vincent's Hospital, Melbourne, VIC, Australia.
Marliese AlexanderPharmacy Department, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Kate BurburySir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.
Prem Prakash JayaramanFactory of the Future and Digital Innovation Lab, School of Science, Computing and Engineering Technologies, Swinburne University of Technology, Melbourne, VIC, Australia.
Nilmini WickramasingheOptus Digital Health, La Trobe University, Melbourne, VIC, Australia.
Penelope SchofieldSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.

Funding

Digital Health Cooperative Research Centre, Swinburne University of Technology and Peter MacCallum Cancer Centre DHCRC-0043
6 · The paper itself

Abstract

purposeMedication non-adherence is a well-recognised problem in cancer care, negatively impacting health outcomes and healthcare resources. Patient-related factors influencing medication adherence (MA) are complicated and interrelated. There is a need for qualitative research to better understand their underlying interaction processes and patients' needs to facilitate the development of effective patient-tailored complex interventions. This study aimed to explore experiences, perceptions, and needs relating to MA and side effect management of patients who are self-administering anti-cancer treatment.

methodsSemi-structured audio-recorded interviews with patients who have haematological cancer were conducted. A comparative, iterative, and predominantly inductive thematic analysis approach was employed.

resultsTwenty-five patients from a specialist cancer hospital were interviewed. While self-administering cancer medications at home, patients' motivation to adhere was affected by cancer-related physical reactions, fears, cancer literacy and beliefs, and healthcare professional (HCP) and informal support. Patients desired need for regular follow-ups from respectful, encouraging, informative, responsive, and consistent HCPs as part of routine care. Motivated patients can develop high adherence and side effect self-management over time, especially when being supported by HCPs and informal networks.

conclusionPatients with cancer need varied support to medically adhere to and manage side effects at home. HCPs should adapt their practices to meet the patients' expectations to further support them during treatment. We propose a multi-dimensional and technology- and theory-based intervention, which incorporates regular HCP consultations providing tailored education and support to facilitate and maintain patient MA and side effect self-management.

Indexed as

Drug-Related Side Effects and Adverse ReactionsNeoplasmsHumansMedication AdherenceQualitative ResearchTabletsTabletsMedication adherenceOral anti-cancerQualitative researchSelf-managementSide effects

Identifiers

PMID37934298
PMCPMC10630231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.