Evidence map›Paper›PMID 37934295›Full record

ArticleMagma (New York, N.Y.)2024

Cranial bone imaging using ultrashort echo-time bone-selective MRI as an alternative to gradient-echo based "black-bone" techniques.

Nada Kamona, Brandon C Jones, Hyunyeol Lee, Hee Kwon Song, Chamith S Rajapakse, Connor S Wagner, Scott P Bartlett, Felix W Wehrli

Open access · greenAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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  11. Automated Craniofacial Biometry with 3D T2w Fetal MRI.medRxiv : the preprint server for health sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nada KamonaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Brandon C JonesDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hyunyeol LeeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hee Kwon SongDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Chamith S RajapakseDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Connor S WagnerDivision of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Scott P BartlettDivision of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Felix W WehrliDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Felix.Wehrli@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0003-3430-1840
University of Pennsylvania · USChildren's Hospital of Philadelphia · USKyungpook National University · KR

Funding

Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
Solid-State MRI as a Noninvasive Alternative to Computed Tomography for Craniofacial ImagingR21DE028417 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2019 to 2020
$457k
Bone health assessment through magnetic susceptibility mappingF31AR079925 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI JONES, BRANDON CLINTON · 2021 to 2024
$112k
NIAMS NIH HHS F31 AR079925NIBIB NIH HHS T32 EB020087NIDCR NIH HHS R21 DE028417
6 · The paper itself

Abstract

objectivesCT is the clinical standard for surgical planning of craniofacial abnormalities in pediatric patients. This study evaluated three MRI cranial bone imaging techniques for their strengths and limitations as a radiation-free alternative to CT.

methodsTen healthy adults were scanned at 3 T with three MRI sequences: dual-radiofrequency and dual-echo ultrashort echo time sequence (DURANDE), zero echo time (ZTE), and gradient-echo (GRE). DURANDE bright-bone images were generated by exploiting bone signal intensity dependence on RF pulse duration and echo time, while ZTE bright-bone images were obtained via logarithmic inversion. Three skull segmentations were derived, and the overlap of the binary masks was quantified using dice similarity coefficient. Craniometric distances were measured, and their agreement was quantified.

resultsThere was good overlap of the three masks and excellent agreement among craniometric distances. DURANDE and ZTE showed superior air-bone contrast (i.e., sinuses) and soft-tissue suppression compared to GRE. DISCUSSIONS: ZTE has low levels of acoustic noise, however, ZTE images had lower contrast near facial bones (e.g., zygomatic) and require effective bias-field correction to separate bone from air and soft-tissue. DURANDE utilizes a dual-echo subtraction post-processing approach to yield bone-specific images, but the sequence is not currently manufacturer-supported and requires scanner-specific gradient-delay corrections.

Indexed as

Image Processing, Computer-AssistedSkullAdultChildHumansMagnetic Resonance ImagingBlack-bone MRICranial boneUTEZTE

Identifiers

PMID37934295
PMCPMC10923077
OpenAlexW4388455893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.