Evidence map›Paper›PMID 37934090›Full record

Observational studyJournal of diabetes investigation2024

Effects of hybrid closed-loop system on glycemic control and psychological aspects in persons with type 1 diabetes treated with sensor-augmented pump: A prospective single-center observational study.

Tomoaki Akiyama, Tadashi Yamakawa, Kazuki Orime, Masahiro Ichikawa, Marina Harada, Takumi Netsu, Ryoichi Akamatsu, Keita Nakamura, Satoru Shinoda, Yasuo Terauchi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of diabetes investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Observational
  4. Article
  5. Observational
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tomoaki AkiyamaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.ORCID https://orcid.org/0000-0002-9942-9661
Tadashi YamakawaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.ORCID https://orcid.org/0000-0001-6329-0939
Kazuki OrimeDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Masahiro IchikawaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Marina HaradaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Takumi NetsuDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Ryoichi AkamatsuDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Keita NakamuraDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, Japan.
Satoru ShinodaDepartment of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
Yasuo TerauchiDepartment of Endocrinology and Metabolism, Yokohama City University School of Medicine, Yokohama, Japan.
Yokohama City University Medical Center · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThis study evaluated the effects of the Medtronic MiniMed 770G hybrid closed-loop system on glycemic control and psychological aspects in persons with type 1 diabetes mellitus. MATERIALS AND

methodsThis 3-month prospective observational study included 22 participants with type 1 diabetes mellitus who used the Medtronic MiniMed 640G predictive low-glucose suspend system and were switched to the 770G system. Time in the range of 70-180 mg/dL and glycated hemoglobin levels were evaluated; satisfaction, emotional distress and quality of life were assessed using self-reported questionnaires, including the Diabetes Treatment Satisfaction Questionnaire Status, Problem Area in Diabetes and Diabetes Therapy-Related Quality of Life.

resultsTime in the range of 70-180 mg/dL increased (63.5 ± 13.4 to 73.0 ± 10.9% [mean ± standard deviation], P = 0.0010), and time above the range of 181-250 mg/dL decreased (26.9 ± 8.9 to 19.6 ± 7.1%, P < 0.0005). Glycated hemoglobin levels decreased (7.7 ± 1.0 to 7.2 ± 0.8%, P = 0.0021). The percentage of participants with time below the range of 54-69 mg/dL <4% of readings increased from 91% to 100% (P < 0.0005). No significant changes were detected in the satisfaction, emotional distress and quality of life levels, but increased sensor calibration might be related to worsened emotional distress and quality of life.

conclusionsThe hybrid closed-loop system decreased hyperglycemia and minimized hypoglycemia, but did not improve psychological aspects compared with the predictive low-glucose suspend system, probably because sensor calibration was increased.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseGlycated HemoglobinGlycemic ControlHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsProspective StudiesQuality of LifeTreatment OutcomeBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinBlood glucoseInsulin infusion systemsType 1 diabetes mellitus

Identifiers

PMID37934090
PMCPMC10804894
OpenAlexW4388453751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.