Evidence map›Paper›PMID 37933385›Full record

ReviewExploration (Beijing, China)2023

Aptamer-functionalized field-effect transistor biosensors for disease diagnosis and environmental monitoring.

Jingfeng Wang, Duo Chen, Wanting Huang, Nianjun Yang, Quan Yuan, Yanbing Yang

Abstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Biosensing With Nanofluidics.Exploration (Beijing, China) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingfeng WangCollege of Chemistry and Molecular Sciences, Institute of Molecular Medicine Renmin Hospital of Wuhan University, School of Microelectronics, Wuhan University Wuhan China.
Duo ChenCollege of Chemistry and Molecular Sciences, Institute of Molecular Medicine Renmin Hospital of Wuhan University, School of Microelectronics, Wuhan University Wuhan China.
Wanting HuangCollege of Chemistry and Molecular Sciences, Institute of Molecular Medicine Renmin Hospital of Wuhan University, School of Microelectronics, Wuhan University Wuhan China.
Nianjun YangDepartment of Chemistry, Insititute of Materials Research Hasselt University Hasselt Belgium.ORCID https://orcid.org/0000-0002-5558-2314
Quan YuanMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha China.ORCID https://orcid.org/0000-0002-3085-431X
Yanbing YangCollege of Chemistry and Molecular Sciences, Institute of Molecular Medicine Renmin Hospital of Wuhan University, School of Microelectronics, Wuhan University Wuhan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nano-biosensors that are composed of recognition molecules and nanomaterials have been extensively utilized in disease diagnosis, health management, and environmental monitoring. As a type of nano-biosensors, molecular specificity field-effect transistor (FET) biosensors with signal amplification capability exhibit prominent advantages including fast response speed, ease of miniaturization, and integration, promising their high sensitivity for molecules detection and identification. With intrinsic characteristics of high stability and structural tunability, aptamer has become one of the most commonly applied biological recognition units in the FET sensing fields. This review summarizes the recent progress of FET biosensors based on aptamer functionalized nanomaterials in medical diagnosis and environmental monitoring. The structure, sensing principles, preparation methods, and functionalization strategies of aptamer modified FET biosensors were comprehensively summarized. The relationship between structure and sensing performance of FET biosensors was reviewed. Furthermore, the challenges and future perspectives of FET biosensors were also discussed, so as to provide support for the future development of efficient healthcare management and environmental monitoring devices.

Indexed as

aptamerbiosensordisease diagnosisenvironmental monitoringfield‐effect transistor

Identifiers

PMID37933385
PMCPMC10624392

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.