Evidence map›Paper›PMID 37933379›Full record

ReviewExploration (Beijing, China)2023

Recent development of pH-responsive theranostic nanoplatforms for magnetic resonance imaging-guided cancer therapy.

Xu Li, Renye Yue, Guoqiang Guan, Cheng Zhang, Ying Zhou, Guosheng Song

Abstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
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  6. Antibody-Empowered Nanomedicine for Precise Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
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  15. Skin-compatible CarbopolMacromolecular materials and engineering · 2025
    Article
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  17. Article
  18. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xu LiState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.
Renye YueState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.
Guoqiang GuanState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.
Cheng ZhangState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.
Ying ZhouState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.
Guosheng SongState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University Changsha P. R. China.ORCID https://orcid.org/0000-0001-5628-6245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acidic characteristic of the tumor site is one of the most well-known features and provides a series of opportunities for cancer-specific theranostic strategies. In this regard, pH-responsive theranostic nanoplatforms that integrate diagnostic and therapeutic capabilities are highly developed. The fluidity of the tumor microenvironment (TME), with its temporal and spatial heterogeneities, makes noninvasive molecular magnetic resonance imaging (MRI) technology very desirable for imaging TME constituents and developing MRI-guided theranostic nanoplatforms for tumor-specific treatments. Therefore, various MRI-based theranostic strategies which employ assorted therapeutic modes have been drawn up for more efficient cancer therapy through the raised local concentration of therapeutic agents in pathological tissues. In this review, we summarize the pH-responsive mechanisms of organic components (including polymers, biological molecules, and organosilicas) as well as inorganic components (including metal coordination compounds, metal oxides, and metal salts) of theranostic nanoplatforms. Furthermore, we review the designs and applications of pH-responsive theranostic nanoplatforms for the diagnosis and treatment of cancer. In addition, the challenges and prospects in developing theranostic nanoplatforms with pH-responsiveness for cancer diagnosis and therapy are discussed.

Indexed as

cancer therapyMRI‐guidednanoplatformpH‐responsive

Identifiers

PMID37933379
PMCPMC10624388

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.