Evidence map›Paper›PMID 37933376›Full record

ArticleExploration (Beijing, China)2023

Microglial targeted therapy relieves cognitive impairment caused by

Wenlong Zhang, Huaqing Chen, Liuyan Ding, Jie Huang, Mengran Zhang, Yan Liu, Runfang Ma, Shaohui Zheng, Junwei Gong, Juan C Piña-Crespo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Wenlong ZhangDepartment of Neurology The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Huaqing ChenShenzhen Key Laboratory of Gene and Antibody Therapy Center for Biotechnology and Biomedicine State Key Laboratory of Chemical Oncogenomics State Key Laboratory of Health Sciences and Technology Institute of Biopharmaceutical and Health Engineering Shenzhen International Graduate School Tsinghua University Shenzhen China.
Liuyan DingDepartment of Neurology The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Jie HuangKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.
Mengran ZhangKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.
Yan LiuSchool of Traditional Chinese Medicine Jinan University Guangzhou China.
Runfang MaKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.
Shaohui ZhengKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.
Junwei GongKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.
Juan C Piña-CrespoDegenerative Diseases Program Center for Genetic Disorders and Aging Research Sanford Burnham Prebys Medical Discovery Institute La Jolla California USA.
Yunlong ZhangKey Laboratory of Neurological Function and Health School of Basic Medical Sciences Guangzhou Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-2447-9138
Westlake University · CNGuangzhou Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNJinan University · CNSanford Burnham Prebys Medical Discovery Institute · USShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contactin-associated protein-like 4 (Cntnap4) is critical for GABAergic transmission in the brain. Impaired Cntnap4 function is implicated in neurological disorders, such as autism; however, the role of Cntnap4 on memory processing is poorly understood. Here, we demonstrate that hippocampal

Indexed as

Cntnap4memory processingmicroglial targeted deliveryPLX3397pro‐inflammatory response

Identifiers

PMID37933376
PMCPMC10624376
OpenAlexW4376140044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.