Evidence map›Paper›PMID 37933290›Full record

ArticleSAGE open medicine2023

Bacterial profile and extended spectrum beta lactamase screening of urinary tract infection among asymptomatic and symptomatic pregnant women attending antenatal care in ALERT Hospital, Addis Ababa, Ethiopia.

Molla Getie, Solomon Gebre-Selassie, Yemeserach Getu, Setognal Birara, Chalachew Tiruneh, Abtie Abebaw, Yibeltal Akelew, Getu Abeje, Aklesya Enkobahry

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Molla GetieDepartments of Medical Laboratory Science, Injibara University, Injibara, Ethiopia.ORCID https://orcid.org/0000-0003-0628-7260
Solomon Gebre-SelassieDepartment of Microbiology, Immunology and Parasitology, Addis Ababa University, Addis Ababa, Ethiopia.
Yemeserach GetuDepartment of Medical Laboratory/Microbiology Unit, ALERT Hospital, Addis Ababa, Ethiopia.
Setognal BiraraDepartment of Epidemiology and Biostatics', University of Gonder, Gonder, Ethiopia.ORCID https://orcid.org/0000-0001-7565-7515
Chalachew TirunehDepartments of Biomedical Science, Injibara University, Injibara, Ethiopia.ORCID https://orcid.org/0000-0003-1976-840X
Abtie AbebawDepartment of Medical Laboratory Science, Debere Markose University, Debere Markose, Ethiopia.ORCID https://orcid.org/0000-0002-8132-4001
Yibeltal AkelewDepartment of Medical Laboratory Science, Debere Markose University, Debere Markose, Ethiopia.
Getu AbejeDepartments of Biomedical Science, Samara University, Samara, Ethiopia.
Aklesya EnkobahryDepartments of Biomedical Science, Injibara University, Injibara, Ethiopia.
Jigjiga University · ETDebre Markos University · ETAddis Ababa University · ETAll Africa Leprosy Tuberculosis and Rehabilitation Training Centre · ETSamara University · ETUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The occurrence of extended spectrum beta lactamase-producing uropathogens, especially in pregnant women can result in life-threatening condition and morbidity for both the mother and the newborn due to very limited drug options for treatment of these pathogens. The aim of this study was to determine the bacterial profile, associated factors, and their antimicrobial susceptibility patterns and to identify extended spectrum beta lactamase-producing bacterial uropathogens. Methods: A hospital-based cross-sectional study was conducted from July to September 2018 on a total of 177 pregnant women with and without symptoms of urinary tract infection at ALERT Hospital, Addis Ababa, Ethiopia. From these study participants, 72 have symptoms, whereas 105 have no symptoms. All urine samples were inoculated onto cysteine lactose electrolyte deficient medium and MacConkey agar. Colonies were counted to check the presence of significant bacteriuria. Pure isolates of bacterial pathogen were characterized and identified at species level by colony morphology, gram stain, and standard biochemical procedures. All Gram-negative isolates were put into Muller-Hinton agar plates for antibiotic susceptibility test by Kirby-Bauer disc diffusion technique. Extended spectrum beta lactamase was detected using double-disk synergy methods on Muller-Hinton agar. The data were double entered into epidemiological Information system and analyzed using Statistical Package for Social Science version 26. Results: The overall proportion of urinary tract infection among pregnant women was 14.7% ( Conclusions: Majority of extended spectrum beta lactamase-producing isolates exhibited co-resistance to other commonly prescribed antibiotics. This indicates that the option of treatment for these pathogens rapidly decreased from time to time which results serious life-threatening conditions, especially in mother and newborn unless the appropriate measure is taken.

Indexed as

Addis Ababaantibiotic resistanceEthiopiaExtended spectrum beta lactamasespregnancyurinary tract infectionuropathogen

Identifiers

PMID37933290
PMCPMC10625732
OpenAlexW4388348815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.