Evidence map›Paper›PMID 37933286›Full record

ArticleExploration (Beijing, China)2023

The pharmacology and therapeutic role of cannabidiol in diabetes.

Jin Zhang, Cong Lin, Sha Jin, Hongshuang Wang, Yibo Wang, Xiubo Du, Mark R Hutchinson, Huiying Zhao, Le Fang, Xiaohui Wang

Open access · goldAbstract read
In one paragraph

Article in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. The Role of Cannabidiol in Liver Disease: A Systemic Review.International journal of molecular sciences · 2024
    Pooled it
  3. Bioactives in Food-As-Medicine for Special Medical Purposes.Advances in nutrition (Bethesda, Md.) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Engineered extracellular vesicles as "supply vehicles" to alleviate type 1 diabetes.Extracellular vesicles and circulating nucleic acids · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Jin ZhangDepartment of Geriatrics The First Hospital of Jilin University Changchun People's Republic of China.ORCID https://orcid.org/0000-0003-3860-3934
Cong LinLaboratory of Chemical Biology, Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun People's Republic of China.
Sha JinLaboratory of Chemical Biology, Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun People's Republic of China.
Hongshuang WangLaboratory of Chemical Biology, Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun People's Republic of China.
Yibo WangLaboratory of Chemical Biology, Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun People's Republic of China.
Xiubo DuShenzhen Key Laboratory of Marine Biotechnology and Ecology College of Life Sciences and Oceanography Shenzhen University Shenzhen People's Republic of China.
Mark R HutchinsonDiscipline of Physiology Adelaide Medical School University of Adelaide The Commonwealth of Australia Adelaide Australia.
Huiying ZhaoDepartment of Geriatrics The First Hospital of Jilin University Changchun People's Republic of China.
Le FangDepartment of Neurology The China-Japan Union Hospital of Jilin University Changchun People's Republic of China.
Xiaohui WangState Key Laboratory of Natural and Biomimetic Drugs Peking University Beijing People's Republic of China.ORCID https://orcid.org/0000-0002-3415-5612
Chinese Academy of Sciences · CNJilin University · CNUniversity of Science and Technology of China · CNShenzhen University · CNThe University of Adelaide · AUUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, cannabidiol (CBD), a non-psychotropic cannabinoid, has garnered substantial interest in drug development due to its broad pharmacological activity and multi-target effects. Diabetes is a chronic metabolic disease that can damage multiple organs in the body, leading to the development of complications such as abnormal kidney function, vision loss, neuropathy, and cardiovascular disease. CBD has demonstrated significant therapeutic potential in treating diabetes mellitus and its complications owing to its various pharmacological effects. This work summarizes the role of CBD in diabetes and its impact on complications such as cardiovascular dysfunction, nephropathy, retinopathy, and neuropathy. Strategies for discovering molecular targets for CBD in the treatment of diabetes and its complications are also proposed. Moreover, ways to optimize the structure of CBD based on known targets to generate new CBD analogues are explored.

Indexed as

activity‐based protein profilingcannabidioldiabetesdrug discoverythermal proteome profiling

Identifiers

PMID37933286
PMCPMC10582612
OpenAlexW4384071012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.