Evidence map›Paper›PMID 37933085›Full record

Trial reportJournal of sleep research2024

Daytime symptom trajectories among adults with stable heart failure and insomnia: evidence from a randomised controlled trial of cognitive behavioural therapy for insomnia.

Samantha Conley, Sangchoon Jeon, Zequan Wang, Christine Tocchi, Sarah Linsky, Meghan O'Connell, Nancy S Redeker

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of sleep research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Brain connectivity changes associated with acute sleep deprivation: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samantha ConleyMayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-4501-5244
Sangchoon JeonYale University, New Haven, Connecticut, USA.
Zequan WangUniversity of Connecticut, Storrs, Connecticut, USA.
Christine TocchiUniversity of Connecticut, Storrs, Connecticut, USA.
Sarah LinskyYale University, New Haven, Connecticut, USA.
Meghan O'ConnellUniversity of Connecticut, Storrs, Connecticut, USA.
Nancy S RedekerUniversity of Connecticut, Storrs, Connecticut, USA.

Funding

Rest Activity Rhythms and Cognitive Function in Stable Heart FailureR01NR016191 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S · 2015 to 2019
$3.6M
Yale Center for Sleep Disturbance in Acute and Chronic ConditionsP20NR014126 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S, YAGGI, HENRY KLAR · 2012 to 2016
$1.4M
NINR NIH HHS P20 NR014126NINR NIH HHS P20NR014126NINR NIH HHS R01 NR016191NINR NIH HHS R01NR016191
6 · The paper itself

Abstract

People with heart failure (HF) experience a high symptom burden and prevalent insomnia. However, little is known about daytime symptom trajectories after cognitive behavioural therapy for insomnia (CBT-I). In this study we describe: (1) daytime symptom trajectories among adults with insomnia and stable HF over 1 year, (2) how symptom trajectories differ between CBT-I versus HF self-management interventions, and (3) associations between demographic, clinical, and sleep characteristics, perceived stress, health-related quality of life (HRQoL), functional performance and daytime symptoms trajectories. We retrospectively analysed data from a randomised controlled trial of CBT-I versus HF self-management (NCT0266038). We measured sleep, perceived stress, HRQoL, and functional performance at baseline and symptoms at baseline, 3, 6, and 12 months. We conducted group-based trajectory modelling, analysis of variance, chi-square, and proportional odds models. Among 175 participants (mean [standard deviation] age 63.0 [12.9] years, 57.1% male, 76% White), we found four daytime symptom trajectories: (A) low improving symptoms (38.3%); (B) low psychological symptoms and high improving physical symptoms (22.8%); (C) high improving symptoms (24.0%); and (D) high not improving symptoms (14.9%). The CBT-I versus the HF self-management group had higher odds of belonging to Group A compared to other trajectories after controlling for baseline fatigue (odds ratio = 3.27, 95% confidence interval 1.39-7.68). The difference between the CBT-I and the HF self-management group was not statistically significant after controlling for baseline characteristics. Group D had the highest body mass index, perceived stress, and insomnia severity and the lowest cognitive ability, HRQoL, and functional performance. Research is needed to further evaluate factors contributing to symptom trajectories.

Indexed as

Cognitive Behavioral TherapyHeart FailureQuality of LifeSleep Initiation and Maintenance DisordersAgedFemaleHumansMaleMiddle AgedRetrospective StudiesStress, Psychologicalactigraphydepressionfatiguehealth‐related quality of lifeheart failureinsomniapainself‐managementsleepsleepinessstress

Identifiers

PMID37933085
PMCPMC12824628

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.