Evidence map›Paper›PMID 37932609›Full record

ArticleMolecular imaging and biology2024

Quantitative and Qualitative Assessment of Urinary Activity of

Phillip H Kuo, Rick Hermsen, Ross Penny, Ernst J Postema

2 registry-linked trialsAbstract read
In one paragraph

Article in Molecular imaging and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04186819 phase3completednot on this map

A Prospective, Phase 3, Multi Center, Single-arm, Imaging Study Investigating the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) Positron Emission Tomography (PET) Ligand in Men With Newly Diagnosed Prostate Cancer

TypeinterventionalSponsorBlue Earth DiagnosticsRan2020 to 2021Enrolled356ConditionsProstate CancerArmsrhPSMA-7.3 (18F) Injection, Positron Emission Tomography scan
NCT04186845 phase3completednot on this map

A Prospective, Phase 3, Multi Center, Single-arm, Imaging Study Investigating the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) PET Ligand in Men With Suspected Prostate Cancer Recurrence Based on Elevated PSA Following Prior Therapy (SPOTLIGHT)

TypeinterventionalSponsorBlue Earth DiagnosticsRan2020 to 2021Enrolled391ConditionsProstate CancerArmsrhPSMA-7.3 (18F) Injection, Positron emission tomography scan
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. An intra-patient contemporaneous comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. True-PositiveJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Trial
  3. A Pilot Study ofThe Prostate · 2026
    Article
  4. Mitigating bladder signal inEJNMMI physics · 2026
    Article
  5. Bladder activity of different PSMA PET radioligands and impact of furosemide.American journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Review
  7. Biochemical failure-free survival ofScientific reports · 2025
    Article
  8. Article
  9. Article
  10. Normal-organ distribution of PSMA-targeting PET radiopharmaceuticalAmerican journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Phillip H KuoDepartments of Medical Imaging, Medicine, and Biomedical Engineering, University of Arizona, Tucson, AZ, USA. pkuo@arizona.edu.
Rick HermsenDepartment of Nuclear Medicine, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Ross PennyBlue Earth Diagnostics Ltd, Oxford, UK.
Ernst J PostemaBlue Earth Diagnostics Ltd, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of urinary activity on interpretation of PROCEDURES: Newly diagnosed or recurrent prostate cancer patients enrolled in LIGHTHOUSE (NCT04186819) or SPOTLIGHT (NCT04186845), respectively, underwent PET/CT 50-70 min after intravenous administration of 296 MBq

resultsIn total, 712/718 scans were evaluable. Reasons for exclusion were cystectomy, renal failure, or urinary catheter in situ (n = 2 each). The median bladder SUV

conclusions

Indexed as

Positron Emission Tomography Computed TomographyProstatic NeoplasmsArtifactsClinical Trials, Phase III as TopicGallium RadioisotopesHumansMaleRadiopharmaceuticalsGallium RadioisotopesRadiopharmaceuticalsBladderHalo artifactPositron emission tomographyProstatic neoplasmsPSMArhPSMAUrinary activity

Identifiers

PMID37932609
PMCPMC10827967

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.