Evidence map›Paper›PMID 37932543›Full record

Observational studyJournal of general internal medicine2024

The Association of Frailty and Neighborhood Disadvantage with Emergency Department Visits and Hospitalizations in Older Adults.

Kristin M Lenoir, Rajib Paul, Elena Wright, Deepak Palakshappa, Nicholas M Pajewski, Amresh Hanchate, Jaime M Hughes, Jennifer Gabbard, Brian J Wells, Michael Dulin and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of general internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  5. Accountable care organizations and Medicare payments for residents with ADRD in disadvantaged neighborhoods.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristin M LenoirDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA. klenoir@wakehealth.edu.
Rajib PaulDepartment of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA.
Elena WrightCenter for Healthcare Innovation, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Deepak PalakshappaSection of General Internal Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Nicholas M PajewskiDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Amresh HanchateDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jaime M HughesDepartment of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jennifer GabbardSection of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Brian J WellsDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Michael DulinDepartment of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA.
Jennifer HoulihanValue Based Care and Population Health, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA.
Kathryn E CallahanCenter for Healthcare Innovation, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Pepper OAIC Coordinating CenterU24AG059624 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DALANE W KITZMAN · 2018 to 2026
$6.0M
Shared and novel contributors to risk of stroke and stroke recurrence in a multiethnic population – the role of social determinants of health, genetics, and epigeneticsR01NS136542 · NINDS · UNIVERSITY OF VIRGINIA · PI HSU, FANG-CHI, KEENE, KEITH L · 2024 to 2025
$1.2M
Identifying Frailty in Primary Care: Implementation of an Electronic Medical Record-based Frailty IndexK76AG059986 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CALLAHAN, KATHRYN · 2018 to 2022
$1.2M
Implementation Strategies to Promote Advance Care Planning among Persons Living with ADRD and those with Mild Cognitive Impairment in Outpatient Primary Care PracticesK23AG070234 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jennifer Lynn Gabbard · 2022 to 2026
$879k
Mobile Technology for Primary Care to Address Food Insecurity and Improve Cardiovascular HealthK23HL146902 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PALAKSHAPPA, DEEPAK · 2020 to 2024
$776k
NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1TR001420NHLBI NIH HHS K23 HL146902NIA NIH HHS K23 AG070234NIA NIH HHS K76 AG059986NIA NIH HHS P30 AG021332NIA NIH HHS U24 AG059624NINDS NIH HHS R01 NS136542
6 · The paper itself

Abstract

backgroundRisk stratification and population management strategies are critical for providing effective and equitable care for the growing population of older adults in the USA. Both frailty and neighborhood disadvantage are constructs that independently identify populations with higher healthcare utilization and risk of adverse outcomes.

objectiveTo examine the joint association of these factors on acute healthcare utilization using two pragmatic measures based on structured data available in the electronic health record (EHR).

designIn this retrospective observational study, we used EHR data to identify patients aged ≥ 65 years at Atrium Health Wake Forest Baptist on January 1, 2019, who were attributed to affiliated Accountable Care Organizations. Frailty was categorized through an EHR-derived electronic Frailty Index (eFI), while neighborhood disadvantage was quantified through linkage to the area deprivation index (ADI). We used a recurrent time-to-event model within a Cox proportional hazards framework to examine the joint association of eFI and ADI categories with healthcare utilization comprising emergency visits, observation stays, and inpatient hospitalizations over one year of follow-up. KEY

resultsWe identified a cohort of 47,566 older adults (median age = 73, 60% female, 12% Black). There was an interaction between frailty and area disadvantage (P = 0.023). Each factor was associated with utilization across categories of the other. The magnitude of frailty's association was larger than living in a disadvantaged area. The highest-risk group comprised frail adults living in areas of high disadvantage (HR 3.23, 95% CI 2.99-3.49; P < 0.001). We observed additive effects between frailty and living in areas of mid- (RERI 0.29; 95% CI 0.13-0.45; P < 0.001) and high (RERI 0.62, 95% CI 0.41-0.83; P < 0.001) neighborhood disadvantage.

conclusionsConsidering both frailty and neighborhood disadvantage may assist healthcare organizations in effectively risk-stratifying vulnerable older adults and informing population management strategies. These constructs can be readily assessed at-scale using routinely collected structured EHR data.

Indexed as

FrailtyAgedEmergency Room VisitsFemaleHospitalizationHumansMaleNeighborhood CharacteristicsRetrospective Studiesarea deprivation indexelectronic health recordsfrailtyhealth servicesrisk stratification.social determinants of health

Identifiers

PMID37932543
PMCPMC10973290

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.