Evidence map›Paper›PMID 37932379›Full record

ReviewNature biomedical engineering2025

A framework for integrating artificial intelligence for clinical care with continuous therapeutic monitoring.

Emma Chen, Shvetank Prakash, Vijay Janapa Reddi, David Kim, Pranav Rajpurkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  17. Beyond Flexible: Unveiling the Next Era of Flexible Electronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emma ChenHarvard John A. Paulson School of Engineering and Applied Sciences, Boston, MA, USA. yingchen@g.harvard.edu.ORCID http://orcid.org/0000-0002-7528-5229
Shvetank PrakashHarvard John A. Paulson School of Engineering and Applied Sciences, Boston, MA, USA.ORCID http://orcid.org/0000-0002-0748-5157
Vijay Janapa Reddi *Harvard John A. Paulson School of Engineering and Applied Sciences, Boston, MA, USA.
David Kim *Department of Emergency Medicine, Stanford School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0151-5121
Pranav Rajpurkar *Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. pranav_rajpurkar@hms.harvard.edu.ORCID http://orcid.org/0000-0002-8030-3727
Harvard University · USStanford Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex relationships between continuously monitored health signals and therapeutic regimens can be modelled via machine learning. However, the clinical implementation of the models will require changes to clinical workflows. Here we outline ClinAIOps ('clinical artificial-intelligence operations'), a framework that integrates continuous therapeutic monitoring and the development of artificial intelligence (AI) for clinical care. ClinAIOps leverages three feedback loops to enable the patient to make treatment adjustments using AI outputs, the clinician to oversee patient progress with AI assistance, and the AI developer to receive continuous feedback from both the patient and the clinician. We lay out the central challenges and opportunities in the deployment of ClinAIOps by means of examples of its application in the management of blood pressure, diabetes and Parkinson's disease. By enabling more frequent and accurate measurements of a patient's health and more timely adjustments to their treatment, ClinAIOps may substantially improve patient outcomes.

Indexed as

Artificial IntelligenceBlood PressureDiabetes MellitusHumansMachine LearningMonitoring, PhysiologicParkinson Disease

Identifiers

PMID37932379
OpenAlexW4388425291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.