Trial reportBMJ open respiratory research2023
Efficacy of different respiratory supports to prevent hypoxia during flexible bronchoscopy in patients of COPD: a triple-arm, randomised controlled trial.
Trial report in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Respiratory Support in the Emergency Department: An Updated Systematic Review and Meta-Analysis.Worldviews on evidence-based nursing · 2026Pooled it
- Efficacy and safety of supraglottic jet oxygenation and ventilation in Chinese patients undergoing bronchoscopic procedures: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- The effectiveness of transnasal high flow nasal cannula in bronchoscopy under sedation: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- The safety and efficacy of two different airway management methods for patients undergoing fiberoptic bronchoscopy: a prospective, randomized, controlled clinical trial.BMC anesthesiology · 2025Trial
- Assessment of Conventional Oxygen Therapy, High-Flow Nasal Cannula, and Non-Invasive Ventilation to Secure Bronchofiberoscopy in Patients with Respiratory Acidosis: A Narrative Review and a Proposal for a Protocol in View of a Randomized Multicenter Study.Journal of clinical medicine · 2026Article
- Evaluating lung ventilation via electrical impedance tomography during flexible bronchoscopy with supraglottic jet ventilation: a prospective pilot study.Journal of anesthesia · 2026Article
- High-flow nasal oxygen therapy via a single-prong cannula interface during bronchoscopy in patients with acute respiratory failure: a two-center, open-label, randomized controlled trial.Annals of intensive care · 2026Article
- Evaluation of high flow nasal cannulae during endobronchial ultrasound bronchoscopy (EBUS) in high anaesthetic risk patients: a monocentric prospective study.BMC anesthesiology · 2025Observational
- Evidence on Non-Invasive Respiratory Support During Flexible Bronchoscopy: A Narrative Review.Journal of clinical medicine · 2025Review
- Short-acting βInternal medicine (Tokyo, Japan) · 2025Article
- Laryngeal mask airway or high-flow nasal cannulaERJ open research · 2025Article
- High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients undergoing bronchoscopy: a retrospective study.BMC pulmonary medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with chronic-obstructive-pulmonary-disease (COPD) undergo bronchoscopy for various reasons, and are at relatively higher risk of complications. This study evaluated the efficacy of non-invasive ventilation (NIV) and high-flow-oxygen-therapy (HFOT) compared with conventional-oxygen-therapy (COT) in patients with COPD undergoing bronchoscopy, to prevent hypoxia.
methodsIt was a triple-arm, open-label, randomised controlled trial. Ninety patients with COPD were randomly assigned into three intervention arms in 1:1:1 ratio. The incidence of hypoxia, lowest recorded oxygen saturation measured by plethysmography (SpO
resultsMean age of the study population was 61.71±7.5 years. Out of 90 cases enrolled, 51, 34 and 5 were moderate, severe and very-severe COPD, respectively, as per GOLD (Global Initiative for Chronic Obstructive Lung Disease) classification. Rest of the baseline characteristics were similar. SpO
conclusionNIV and HFOT are superior to COT in preventing hypoxia during bronchoscopy, but NIV is associated with poor patient-tolerance and inferior operator's ease of doing procedure. TRIAL REGISTRATION NUMBER: CTRI/2021/03/032190.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.