Evidence map›Paper›PMID 37931230›Full record

ArticleAntimicrobial agents and chemotherapy2023

Jumbo phages are active against extensively drug-resistant eyedrop-associated

Ana Georgina Cobián Güemes, Pooja Ghatbale, Alisha N Blanc, Chase J Morgan, Andrew Garcia, Jesse Leonard, Lina Huang, Grace Kovalick, Marissa Proost, Megan Chiu and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. The biology of jumbo phages.Nature communications · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Ana Georgina Cobián Güemes *Department of Pathology, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-0755-5864
Pooja Ghatbale *Department of Pathology, University of California San Diego, La Jolla, California, USA.
Alisha N BlancDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Chase J MorganDepartment of Biology, University of California San Diego, La Jolla, California, USA.
Andrew GarciaDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Jesse LeonardDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Lina HuangDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Grace KovalickDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Marissa ProostDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Megan ChiuDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Peiting KuoDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Joseph OhDepartment of Pathology, University of California San Diego, La Jolla, California, USA.
Smruthi KarthikeyanDepartment of Environmental Science and Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California, USA.
Rob KnightDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-0975-9019
Joe PoglianoDepartment of Biology, University of California San Diego, La Jolla, California, USA.
Robert T SchooleyDepartment of Medicine, University of California San Diego, La Jolla, California, USA.
David T PrideDepartment of Pathology, University of California San Diego, La Jolla, California, USA.ORCID 0000-0001-8161-6015
University of California San Diego · USHoward Hughes Medical Institute · USCalifornia Institute of Technology · US

Funding

Howard Hughes Medical Institute (HHMI) 30207345
6 · The paper itself

Abstract

Antibiotic-resistant bacteria present an emerging challenge to human health. Their prevalence has been increasing across the globe due in part to the liberal use of antibiotics that has pressured them to develop resistance. Those bacteria that acquire mobile genetic elements are especially concerning because those plasmids may be shared readily with other microbes that can then also become antibiotic resistant. Serious infections have recently been related to the contamination of preservative-free eyedrops with extensively drug-resistant (XDR) isolates of

Indexed as

BacteriophagesPseudomonas InfectionsPseudomonas PhagesAnti-Bacterial AgentsHumansPlasmidsPseudomonas aeruginosaAnti-Bacterial Agentsantibiotic resistanceextensively drug resistanteye dropsjumbo phagePseudomonas aeruginosa

Identifiers

PMID37931230
PMCPMC10720484
OpenAlexW4388406520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.