Evidence map›Paper›PMID 37930932›Full record

SynthesisAnnals of medicine2023

Endoscopic versus minimally invasive surgical approach for infected necrotizing pancreatitis: a systematic review and meta-analysis of randomized controlled trials.

Penghao Tang, Kamran Ali, Hayat Khizar, Yuanzhi Ni, Zhiwen Cheng, Benfeng Xu, Zhiwen Qin, Wu Zhang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Acute pancreatitis: mechanisms and therapeutic approaches.Signal transduction and targeted therapy · 2026
    Review
  5. Article
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  7. Long-Term All-Cause Mortality After Acute Pancreatitis: Median 7-Year Follow-Up.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Penghao TangGraduate School of Zhejiang, Chinese Medical University, Hangzhou, Zhejiang, China.
Kamran AliDepartment of Oncology, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Zhejiang, China.ORCID 0000-0002-0304-6130
Hayat KhizarDepartment of Oncology, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Zhejiang, China.ORCID 0000-0002-9736-1384
Yuanzhi NiGraduate School of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhiwen ChengGraduate School of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Benfeng XuGraduate School of Zhejiang, Chinese Medical University, Hangzhou, Zhejiang, China.
Zhiwen QinGraduate School of Zhejiang, Chinese Medical University, Hangzhou, Zhejiang, China.
Wu ZhangDepartment of Hepatobiliary Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University, Shulan International Medical College, Zhejiang, China.
Zhejiang University · CNZhejiang Chinese Medical University · CNZhejiang Shuren University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAcute pancreatitis is a common condition of the digestive system, but sometimes it develops into severe cases. In about 10-20% of patients, necrosis of the pancreas or its periphery occurs. Although most have aseptic necrosis, 30% of cases will develop infectious necrotizing pancreatitis. Infected necrotizing pancreatitis (INP) requires a critical treatment approach. Minimally invasive surgical approach (MIS) and endoscopy are the management methods. This meta-analysis compares the outcomes of MIS and endoscopic treatments.

methodsWe searched a medical database until December 2022 to compare the results of endoscopic and MIS procedures for INP. We selected eligible randomized controlled trials (RCTs) that reported treatment complications for the meta-analysis.

resultsFive RCTs comparing a total of 284 patients were included in the meta-analysis. Among them, 139 patients underwent MIS, while 145 underwent endoscopic procedures. The results showed significant differences (

conclusionsEndoscopic management of INP performs better compared to surgical treatment due to its lower complication rate and higher patient life quality.

Indexed as

EndoscopyPancreatitis, Acute NecrotizingHumansNecrosisPancreasRandomized Controlled Trials as TopicTreatment OutcomecomplicationsendoscopyInfected necrotizing pancreatitisminimally invasive surgerynecrosectomy

Identifiers

PMID37930932
PMCPMC10629416
OpenAlexW4388425483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.