Evidence map›Paper›PMID 37930278›Full record

ArticleACS synthetic biology2023

A Multiplex MoClo Toolkit for Extensive and Flexible Engineering of

William M Shaw, Ahmad S Khalil, Tom Ellis

Abstract read
In one paragraph

Article in ACS synthetic biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William M ShawBiological Design Center, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0002-1289-1993
Ahmad S KhalilBiological Design Center, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0002-8214-0546
Tom EllisDepartment of Bioengineering, Imperial College London, London SW7 2AZ, U.K.ORCID 0000-0001-5392-976X

Funding

Synthetic toolkit for precision gene expression control and signal processing in mammalian cellsR01EB029483 · NIBIB · HARVARD UNIVERSITY · PI Ahmad Samir Khalil · 2020 to 2026
$5.0M
NIBIB NIH HHS R01 EB029483
6 · The paper itself

Abstract

Synthetic biology toolkits are one of the core foundations on which the field has been built, facilitating and accelerating efforts to reprogram cells and organisms for diverse biotechnological applications. The yeast

Indexed as

CRISPR-Cas SystemsSaccharomyces cerevisiaeBiotechnologyEcosystemPlasmidsCRISPR-Cas9modular cloningmultiplexSaccharomyces cerevisiaesynthetic biologytoolkit

Identifiers

PMID37930278
PMCPMC10661031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.