Evidence map›Paper›PMID 37930174›Full record

ReviewACS applied bio materials2024

Advances in Nonviral mRNA Delivery Materials and Their Application as Vaccines for Melanoma Therapy.

Bevin Neill, Adriana Retamales Romero, Owen S Fenton

Abstract readReview
In one paragraph

Review in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  4. Characterizing the Impact of the Cell Cycle on mRNA Lipid Nanoparticles.Journal of the American Chemical Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bevin NeillDivision of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Adriana Retamales RomeroDivision of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Owen S FentonDivision of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-5585-9280

Funding

CTSA K12 Program at UNCK12TR004416 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michelle Hernandez, Jonathan J Juliano · 2023 to 2026
$6.5M
Optimization of Tannic Acid Lipid Nanoparticles for a Therapeutic mRNA Vaccine Against MelanomaR21EB034942 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FENTON, OWEN S · 2023 to 2025
$601k
NCATS NIH HHS K12 TR004416NIBIB NIH HHS R21 EB034942
6 · The paper itself

Abstract

Messenger RNA (mRNA) vaccines are promising platforms for cancer immunotherapy because of their potential to encode for a variety of tumor antigens, high tolerability, and capacity to induce strong antitumor immune responses. However, the clinical translation of mRNA cancer vaccines can be hindered by the inefficient delivery of mRNA

Indexed as

Cancer VaccinesMelanomaRNA, MessengerAnimalsBiocompatible MaterialsHumansImmunotherapyMaterials TestingNanoparticlesParticle SizeBiocompatible MaterialsCancer VaccinesRNA, Messengerlipid nanoparticleslipopolyplexesmelanomamRNA vaccinespolymeric nanoparticles

Identifiers

PMID37930174
PMCPMC11220486

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.