Evidence map›Paper›PMID 37930151›Full record

ArticleCancer communications (London, England)2024

Mitochondria-targeted atovaquone promotes anti-lung cancer immunity by reshaping tumor microenvironment and enhancing energy metabolism of anti-tumor immune cells.

Donghai Xiong, Zheng Yin, Mofei Huang, Yian Wang, Micael Hardy, Balaraman Kalyanaraman, Stephen T Wong, Ming You

Open access · goldAbstract readLetter
In one paragraph

Article in Cancer communications (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  5. Review
  6. Frontiers in immunology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Donghai XiongCenter for Cancer Prevention, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.
Zheng YinDepartment of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.
Mofei HuangCenter for Cancer Prevention, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.
Yian WangCenter for Cancer Prevention, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.
Micael HardyAix Marseille Univ, Centre National de la Recherche Scientifique (CNRS), Institut de Chimie Radicalaire (ICR), Unité Mixte de Recherche (UMR) 7273, Marseille, France.
Balaraman KalyanaramanDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Stephen T WongDepartment of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.
Ming YouCenter for Cancer Prevention, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Texas, USA.ORCID 0009-0004-8713-9765
Houston Methodist · USCornell University · USCentre National de la Recherche Scientifique · FRMedical College of Wisconsin · US

Funding

Transfer Application - R01 CA223804 - Chemoimmunoprevention of EGFR-Driven Non-Small Cell Lung CancerR01CA223804 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, LI LILY, YOU, MING · 2018 to 2022
$3.3M
Inhibition of Oral Tumorigenesis by Antitumor BR01CA205633 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI HU, MING, WONG, STUART J · 2017 to 2022
$2.6M
Chemoprevention of lung cancer by targeting lonidamine to mitochondriaR01CA232433 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI KALYANARAMAN, BALARAMAN, KRESTY, LAURA A · 2019 to 2023
$2.0M
Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesisR01CA280746 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MING YOU, Jacek M Zielonka · 2024 to 2026
$1.9M
NCI NIH HHS R01 CA205633NCI NIH HHS R01 CA223804NCI NIH HHS R01 CA232433NCI NIH HHS R01 CA280746
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung NeoplasmsTumor MicroenvironmentAtovaquoneEnergy MetabolismHumansMitochondriaAtovaquone

Identifiers

PMID37930151
PMCPMC10958673
OpenAlexW4388422480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.