Evidence map›Paper›PMID 37930077›Full record

ArticleJournal of bacteriology2023

Regulation of the general stress response sigma factor σ

Roya Akar, Matthias J Fink, Deike J Omnus, Kristina Jonas

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Roya AkarScience for Life Laboratory and Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius , Stockholm, Sweden.
Matthias J FinkScience for Life Laboratory and Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius , Stockholm, Sweden.ORCID 0000-0002-4620-2009
Deike J OmnusScience for Life Laboratory and Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius , Stockholm, Sweden.ORCID 0000-0002-4091-4291
Kristina JonasScience for Life Laboratory and Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius , Stockholm, Sweden.ORCID 0000-0002-1469-4424
Stockholm University · SE

Funding

Science for Life Laboratory (SciLifeLab)Stiftelsen för Strategisk Forskning (SSF) FFL15-0005Vetenskapsrådet (VR) 2016-03300Vetenskapsrådet (VR) 2020-03545
6 · The paper itself

Abstract

importanceRegulated protein degradation is a critical process in all cell types, which contributes to the precise regulation of protein amounts in response to internal and external cues. In bacteria, protein degradation is carried out by ATP-dependent proteases. Although past work revealed detailed insights into the operation principles of these proteases, there is limited knowledge about the substrate proteins that are degraded by distinct proteases and the regulatory role of proteolysis in cellular processes. This study reveals a direct role of the conserved protease Lon in regulating σ

Indexed as

Caulobacter crescentusProtease LaProteolysisBacterial ProteinsGene Expression Regulation, BacterialSigma FactorBacterial ProteinsProtease LaSigma FactorCaulobacter crescentusECF sigma factorgeneral stress responseLon proteaseregulated proteolysis

Identifiers

PMID37930077
PMCPMC10662116
OpenAlexW4388411996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.